Catalog No: ARP31220_P050-Biotin
Size:100ul
Price: $434.00
SKU
ARP31220_P050-Biotin
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PAX2 Antibody - middle region : Biotin (ARP31220_P050-Biotin)

Datasheets/ManualsPrintable datasheet for anti-PAX2 (ARP31220_P050-Biotin) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
ApplicationWB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of Human PAX2
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%
Peptide SequenceSynthetic peptide located within the following region: DPVGSYSINGILGIPRSNGEKRKRDEDVSEGSVPNGDSQSGVDSLRKHLR
Concentration0.5 mg/ml
Blocking PeptideFor anti-PAX2 (ARP31220_P050-Biotin) antibody is Catalog # AAP31220
Publications

Yu, A. L. et al. Hypoxia/reoxygenation and TGF-beta increase alphaB-crystallin expression in human optic nerve head astrocytes. Exp. Eye Res. 84, 694-706 (2007). WB, IHC, ICC/IF, IP, ChIP, Sheep, Bovine, Dog, Pig, Horse, Zebrafish, Rabbit, Human, Rat, Guinea pig, Mouse 17261280

Yu, A. L. et al. Reactivation of optic nerve head astrocytes by TGF-beta2 and H2O2 is accompanied by increased Hsp32 and Hsp47 expression. Invest. Ophthalmol. Vis. Sci. 50, 1707-17 (2009). WB, IHC, ICC/IF, IP, ChIP, Sheep, Bovine, Dog, Pig, Horse, Zebrafish, Rabbit, Human, Rat, Guinea pig, Mouse 18952926

Hurtado, A. et al. Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen. Nature 456, 663-6 (2008). WB, IHC, ICC/IF, IP, ChIP, Sheep, Bovine, Dog, Pig, Horse, Zebrafish, Rabbit, Human, Rat, Guinea pig, Mouse 19005469

Lee, S. B. et al. PAX2 regulates ADAM10 expression and mediates anchorage-independent cell growth of melanoma cells. PLoS One 6, e22312 (2011). WB, IHC, ICC/IF, IP, ChIP, Sheep, Bovine, Dog, Pig, Horse, Zebrafish, Rabbit, Human, Rat, Guinea pig, Mouse 21876729

Viringipurampeer, I. A. et al. Pax2 regulates a fadd-dependent molecular switch that drives tissue fusion during eye development. Hum. Mol. Genet. 21, 2357-69 (2012). WB, IHC, ICC/IF, IP, ChIP, Sheep, Bovine, Dog, Pig, Horse, Zebrafish, Rabbit, Human, Rat, Guinea pig, Mouse 22357656

Palmieri, C. et al. Expression of steroid receptor coactivator 3 in ovarian epithelial cancer is a poor prognostic factor and a marker for platinum resistance. Br. J. Cancer 108, 2039-44 (2013). WB, IHC, ICC/IF, IP, ChIP, Sheep, Bovine, Dog, Pig, Horse, Zebrafish, Rabbit, Human, Rat, Guinea pig, Mouse 23652306

Gene SymbolPAX2
Alias SymbolsFSGS7, PAPRS
NCBI Gene Id5076
Protein NamePaired box protein Pax-2 Ensembl ENSP00000452527
Description of TargetPAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia.
Uniprot IDQ02962
Protein Accession #NP_000269
Nucleotide Accession #NM_000278
Protein Size (# AA)393
Molecular Weight42kDa
Protein InteractionsBBS7; BBS4; BBS2; BBS1; RB1; BRCA1; SFRP2; PAXIP1; WT1; MAPK8IP1; MAPK8; ID2;
  1. What is the species homology for "PAX2 Antibody - middle region : Biotin (ARP31220_P050-Biotin)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish".

  2. How long will it take to receive "PAX2 Antibody - middle region : Biotin (ARP31220_P050-Biotin)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "PAX2 Antibody - middle region : Biotin (ARP31220_P050-Biotin)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PAX2 Antibody - middle region : Biotin (ARP31220_P050-Biotin)"?

    This target may also be called "FSGS7, PAPRS" in publications.

  5. What is the shipping cost for "PAX2 Antibody - middle region : Biotin (ARP31220_P050-Biotin)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PAX2 Antibody - middle region : Biotin (ARP31220_P050-Biotin)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PAX2 Antibody - middle region : Biotin (ARP31220_P050-Biotin)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "42kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PAX2 Antibody - middle region : Biotin (ARP31220_P050-Biotin)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PAX2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PAX2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PAX2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PAX2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PAX2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PAX2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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