PARVA Antibody - C-terminal region (OAAB05910)

Catalog No: OAAB05910

Size:400UL

Western blot analysis of PARVA Antibody (C-term) in mouse bladder tissue lysates (35ug/lane). PARVA (arrow) was detected using the purified Pab.

PARVA Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded human skeletal muscle tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PARVA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: IHC-P,WB
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This PARVA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-351 amino acids from the C-terminal region of human PARVA.
• Predicted Homology Based on Immunogen Sequence: Human; Mouse
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: WB: 1:1000
  IHC-P: 1:10~50

Target Info

• Gene Symbol: PARVA
• Alias Symbols: 2010012A22Rik, 5430400F08Rik, act, actopaxin, Actp, AI225929, alpha-parvin, AU042898, calponin-like integrin-linked kinase-binding protein, CH-IL, CH-ILKBP, matrix-remodeling-associated protein 2, MXRA2, Parvin.
• NCBI Gene Id: 55742|57341|57342
• Protein Name: Alpha-parvin|alpha-parvin [Homo sapiens]
• Description of Target: Plays a role in sarcomere organization and in smooth muscle cell contraction. Required for normal development of the embryonic cardiovascular system, and for normal septation of the heart outflow tract. Plays a role in sprouting angiogenesis and is required for normal adhesion of vascular smooth muscle cells to endothelial cells during blood vessel development (By similarity). Plays a role in the reorganization of the actin cytoskeleton, formation of lamellipodia and ciliogenesis. Plays a role in the establishement of cell polarity, cell adhesion, cell spreading, and directed cell migration.|Plays a role in the reorganization of the actin cytoskeleton, formation of lamellipodia and ciliogenesis. Plays a role in the establishement of cell polarity, cell adhesion, cell spreading, and directed cell migration. Plays a role in sarcomere organization and in smooth muscle cell contraction. Required for normal development of the embryonic cardiovascular system, and for normal septation of the heart outflow tract. Plays a role in sprouting angiogenesis and is required for normal adhesion of vascular smooth muscle cells to endothelial cells during blood vessel development.
• Uniprot ID: Q9EPC1|Q9HB97|Q9NVD7
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_060692.2
• Molecular Weight: 42244