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Catalog No: ARP44851_P050-Biotin
Size:100ul
Price: $434.00
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ARP44851_P050-Biotin
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PARL Antibody - N-terminal region : Biotin (ARP44851_P050-Biotin)

Datasheets/ManualsPrintable datasheet for anti-PARL (ARP44851_P050-Biotin) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
ApplicationIHC, WB
Additional InformationIHC Information: Lane A: Marker. Lane B: Jurkat cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human PARL
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: SLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQ
Concentration0.5 mg/ml
Blocking PeptideFor anti-PARL (ARP44851_P050-Biotin) antibody is Catalog # AAP44851 (Previous Catalog # AAPP25930)
Sample Type Confirmation

PARL is supported by BioGPS gene expression data to be expressed in Jurkat

ReferenceWalder,K., (2005) Diabetologia 48 (3), 459-468
Publications

Yoshioka, H. et al. The role of PARL and HtrA2 in striatal neuronal injury after transient global cerebral ischemia. J. Cereb. Blood Flow Metab. 33, 1658-65 (2013). WB, Rat, Human, Mouse, Dog, Pig, Horse, Rabbit, Guinea pig, Bovine, Zebrafish 23921894

Gene SymbolPARL
Gene Full NamePresenilin associated, rhomboid-like
Alias SymbolsPSARL, PSARL1, RHBDS1, PRO2207, PSENIP2
NCBI Gene Id55486
Protein NamePresenilins-associated rhomboid-like protein, mitochondrial
Description of TargetPARL is a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. PARL may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in its gene has been associated with increased risk for type 2 diabetes.This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.
Uniprot IDQ9H300-2
Protein Accession #NP_001032728
Nucleotide Accession #NM_001037639
Protein Size (# AA)329
Molecular Weight36kDa
Protein InteractionsUBC; PINK1;
  1. What is the species homology for "PARL Antibody - N-terminal region : Biotin (ARP44851_P050-Biotin)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit".

  2. How long will it take to receive "PARL Antibody - N-terminal region : Biotin (ARP44851_P050-Biotin)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "PARL Antibody - N-terminal region : Biotin (ARP44851_P050-Biotin)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PARL Antibody - N-terminal region : Biotin (ARP44851_P050-Biotin)"?

    This target may also be called "PSARL, PSARL1, RHBDS1, PRO2207, PSENIP2" in publications.

  5. What is the shipping cost for "PARL Antibody - N-terminal region : Biotin (ARP44851_P050-Biotin)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PARL Antibody - N-terminal region : Biotin (ARP44851_P050-Biotin)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PARL Antibody - N-terminal region : Biotin (ARP44851_P050-Biotin)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "36kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PARL Antibody - N-terminal region : Biotin (ARP44851_P050-Biotin)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PARL"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PARL"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PARL"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PARL"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PARL"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PARL"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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