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PARL Antibody - N-terminal region : Biotin (ARP44851_P050-Biotin)
Datasheets/Manuals | Printable datasheet for anti-PARL (ARP44851_P050-Biotin) antibody |
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Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit |
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Product Format | Liquid. Purified antibody supplied in 1x PBS buffer. |
Clonality | Polyclonal |
Host | Rabbit |
Conjugation | Biotin |
Application | IHC, WB |
Additional Information | IHC Information: Lane A: Marker. Lane B: Jurkat cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%. |
Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human PARL |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100% |
Peptide Sequence | Synthetic peptide located within the following region: SLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQ |
Concentration | 0.5 mg/ml |
Blocking Peptide | For anti-PARL (ARP44851_P050-Biotin) antibody is Catalog # AAP44851 (Previous Catalog # AAPP25930) |
Sample Type Confirmation | PARL is supported by BioGPS gene expression data to be expressed in Jurkat |
Reference | Walder,K., (2005) Diabetologia 48 (3), 459-468 |
Publications | Yoshioka, H. et al. The role of PARL and HtrA2 in striatal neuronal injury after transient global cerebral ischemia. J. Cereb. Blood Flow Metab. 33, 1658-65 (2013). WB, Rat, Human, Mouse, Dog, Pig, Horse, Rabbit, Guinea pig, Bovine, Zebrafish 23921894 |
Gene Symbol | PARL |
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Gene Full Name | Presenilin associated, rhomboid-like |
Alias Symbols | PSARL, PSARL1, RHBDS1, PRO2207, PSENIP2 |
NCBI Gene Id | 55486 |
Protein Name | Presenilins-associated rhomboid-like protein, mitochondrial |
Description of Target | PARL is a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. PARL may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in its gene has been associated with increased risk for type 2 diabetes.This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Uniprot ID | Q9H300-2 |
Protein Accession # | NP_001032728 |
Nucleotide Accession # | NM_001037639 |
Protein Size (# AA) | 329 |
Molecular Weight | 36kDa |
Protein Interactions | UBC; PINK1; |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "PARL Antibody - N-terminal region : Biotin (ARP44851_P050-Biotin)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit".
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How long will it take to receive "PARL Antibody - N-terminal region : Biotin (ARP44851_P050-Biotin)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
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What buffer format is "PARL Antibody - N-terminal region : Biotin (ARP44851_P050-Biotin)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "PARL Antibody - N-terminal region : Biotin (ARP44851_P050-Biotin)"?
This target may also be called "PSARL, PSARL1, RHBDS1, PRO2207, PSENIP2" in publications.
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What is the shipping cost for "PARL Antibody - N-terminal region : Biotin (ARP44851_P050-Biotin)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "PARL Antibody - N-terminal region : Biotin (ARP44851_P050-Biotin)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "PARL Antibody - N-terminal region : Biotin (ARP44851_P050-Biotin)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "36kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "PARL Antibody - N-terminal region : Biotin (ARP44851_P050-Biotin)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "PARL"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "PARL"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "PARL"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "PARL"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "PARL"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "PARL"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.