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Catalog No: OPCD05971
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OPCD05971
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Datasheets/ManualsPrintable datasheet for PAM Recombinant Protein (OPCD05971)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
Residues: Phe21-Cys288
Subcellular Location: Secreted
Isoelectric Point: 8.8
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolPAM
Gene Full Namepeptidylglycine alpha-amidating monooxygenase
Alias SymbolsPAL;pancreatic peptidylglycine alpha-amidating monooxygenase;peptidyl alpha-amidating enzyme;peptidyl-alpha-hydroxyglycine alpha-amidating lyase;peptidylamidoglycolate lyase;peptidylglycine 2-hydroxylase;peptidyl-glycine alpha-amidating monooxygenase;peptidylglycine alpha-hydroxylating monooxygenase;PHM.
NCBI Gene Id5066
Protein NamePeptidyl-glycine alpha-amidating monooxygenase
Description of TargetBifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity.
Uniprot IDP19021
Protein Accession #NP_000910.2
Nucleotide Accession #NM_000919.3
Protein Size (# AA)Phe21~Cys288
Molecular Weight34kDa
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