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PAK2 Antibody - N-terminal region : FITC (ARP49217_P050-FITC)

100 ul
$289.00
In Stock
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Conjugation Options

ARP49217_P050 Unconjugated

ARP49217_P050-HRP Conjugated

ARP49217_P050-Biotin Conjugated

Gene Symbol:
PAK2
NCBI Gene Id:
5062
Swissprot Id:
Q13177
Protein Accession #:
NP_002568
Alias Symbols:
PAK2,
Replacement Item:
This antibody may replace item sc-11394 from Santa Cruz Biotechnology.
Description of Target:
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
Protein Size (# AA):
524
Molecular Weight:
57kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express PAK2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express PAK2.
Immunogen:
The immunogen is a synthetic peptide directed towards the N-terminal region of Human PAK2
Predicted Species Reactivity:
Human
Peptide Sequence:
Synthetic peptide located within the following region: DNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHK
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution and Storage:
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Concentration:
0.5 mg/ml
Protein Interactions:
RHOJ; SORBS3; CDC42; UBC; NPEPPS; YWHAZ; YWHAH; YWHAG; YWHAE; YWHAB; TGM2; PFAS; PAFAH1B1; LDHB; ZFYVE19; UBFD1; UBE2R2; SCLY; ISOC1; ERP44; SFN; G6PD; EEF2; CKB; CAPNS1; PAK1; PAK2; HSPA5; RIOK3; MYC; APP; SH3RF3; ARHGEF7; SRC; LCK; HCK; RAC1; HIST1H4F;
Blocking Peptide:
For anti-PAK2 (ARP49217_P050-FITC) antibody is Catalog # AAP49217
Datasheets/Manuals:
Printable datasheet for anti-PAK2 (ARP49217_P050-FITC) antibody
Conjugation:
FITC (FAM): Excitation 495 nm/ Emission 520 nm

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