PAK2 Antibody - N-terminal region : Biotin (ARP49217_P050-Biotin)

Catalog No: ARP49217_P050-Biotin

Size:100ul

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Biotin
• Application: WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PAK2
• Purification: Affinity Purified
• Peptide Sequence: Synthetic peptide located within the following region: DNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHK
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-PAK2 (ARP49217_P050-Biotin) antibody is Catalog # AAP49217

Target Info

• Gene Symbol: PAK2
• Alias Symbols: PAK65, PAKgamma
• NCBI Gene Id: 5062
• Description of Target: The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
• Uniprot ID: Q13177
• Protein Accession #: NP_002568
• Protein Size (# AA): 524
• Molecular Weight: 57kDa
• Protein Interactions: RHOJ; SORBS3; CDC42; UBC; NPEPPS; YWHAZ; YWHAH; YWHAG; YWHAE; YWHAB; TGM2; PFAS; PAFAH1B1; LDHB; ZFYVE19; UBFD1; UBE2R2; SCLY; ISOC1; ERP44; SFN; G6PD; EEF2; CKB; CAPNS1; PAK1; PAK2; HSPA5; RIOK3; MYC; APP; SH3RF3; ARHGEF7; SRC; LCK; HCK; RAC1; HIST1H4F;