Catalog No: OPCD05958
Price: $0.00
SKU
OPCD05958
Availability: Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery
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Datasheets/Manuals | Printable datasheet for PAG1 Recombinant Protein (OPCD05958) |
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Predicted Species Reactivity | Rat|Rattus norvegicus |
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Product Format | Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
Host | E.coli |
Conjugation | Unconjugated |
Application | Ctrl (+), SDS-PAGE, WB |
Additional Information | Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) |
:: | Residues: Ile138-Phe357 |
Reconstitution and Storage | 2°C to 8°C|-80°C |
Concentration | 200 ug/mL (prior to lyoph) |
Purity | > 95% |
Source | E.coli |
Tag | N-terminal His Tag |
Gene Symbol | Pag1 |
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Gene Full Name | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 |
Alias Symbols | Cbp;Csk binding protein;csk-binding protein;phosphoprotein associated with glycosphingolipid microdomains 1;phosphoprotein associated with glycosphingolipid-enriched microdomains 1;transmembrane phosphoprotein Cbp. |
NCBI Gene Id | 64019 |
Protein Name | Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 |
Description of Target | Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling. |
Uniprot ID | Q9JM80 |
Protein Accession # | NP_071589.1 |
Nucleotide Accession # | NM_022253.1 |
Protein Size (# AA) | Ile138~Phe357 |
Molecular Weight | 25kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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