Catalog No: OPCD05946
Price: $0.00
SKU
OPCD05946
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Datasheets/Manuals | Printable datasheet for PA2G4 Recombinant Protein (OPCD05946) |
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Predicted Species Reactivity | Homo sapiens|Human |
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Product Format | Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
Host | E.coli |
Conjugation | Unconjugated |
Application | Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot |
Additional Information | Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) |
:: | Residues: Ser2-Asp394 |
Reconstitution and Storage | 2°C to 8°C|-80°C |
Concentration | 200 ug/mL (prior to lyoph) |
Purity | > 95% |
Source | E.coli |
Tag | N-terminal His Tag |
Gene Symbol | PA2G4 |
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Gene Full Name | proliferation-associated 2G4 |
Alias Symbols | cell cycle protein p38-2G4 homolog;EBP1;ErbB-3 binding protein 1;ErbB-3 receptor binding protein;erbB3-binding protein 1;ErbB3-binding protein Ebp1;HG4-1;p38-2G4;proliferation-associated 2G4, 38kD;proliferation-associated 2G4, 38kDa;proliferation-associated protein 2G4. |
NCBI Gene Id | 5036 |
Protein Name | Proliferation-associated protein 2G4 |
Description of Target | May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site) (By similarity). Regulates cell proliferation, differentiation, and survival. Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation (By similarity). |
Uniprot ID | Q9UQ80 |
Protein Accession # | NP_006182.2 |
Nucleotide Accession # | NM_006191.2 |
Protein Size (# AA) | Ser2~Asp394 |
Molecular Weight | 47kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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