Size:400ul
$215.00
Discontinued
SKU
OASE00376
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Conjugation Options

OASE00376-FITC Conjugated

OASE00376-HRP Conjugated

OASE00376-Biotin Conjugated

p90 RSK1 Antibody (OASE00376)

Catalog#: OASE00376
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This product is Genway GWB-0X0007
More Information
Predicted Species Reactivity Human, Mouse, Rat, Bovine
Clonality Polyclonal
Host Rabbit
Application WB, IP
Additional Information Background Info: Detects a ~90kDa protein corresponding to the molecular mass of p90 RSK1 on SDS PAGE immunoblots.
:: Scientific Background: The p90 ribosomal S6 kinase (Rsk) family comprises four mammalian serine/threonine kinases (Rsk1–4). In the past, S6K1 and S6K2 were thought to be the predominant operating S6 kinases, however RSK 1 and 2 have been shown to phosphorylate S6 in response to the ERK pathway, or otherwise known as the extra cellular signal-regulated kinases pathway. RSK 1 in particular is very multifunctional as it participates in nuclear signaling, regulates nuclear factors, regulates several transcription factors like c-Fos, and interacts with the transcriptional coactivator CREB-binding protein. As a result, RSK1 seems to have an important role in cellular growth control and proliferation. (1-5).
:: Certificate of Analysis: 0.25mg/ml was sufficient for detection of 7 in lysates prepared from mouse brain, spleen and intestine.
Reconstitution and Storage Store at -20C. Shipping in Blue Ice or 4C.
Replacement Item This antibody may replace item sc-130870 from Santa Cruz Biotechnology.
Immunogen Human p90 RSK1 C-terminal peptide, conjugated to KLH
Purification Rabbit immunoglobulin
Concentration 250ug/mL
Datasheets/Manuals Printable datasheet for OASE00376
Dilution 1ug/mL (WB)
Target Reference 1. Roux, P. (2007). UCSD-Nature Molecule Pages. 2. Fro¨din, M. and Gammeltoft, S. (1999) Mol. Cell.
Endocrinol. 151: 65-77.
3. Merienne, K. et al. (1998) J. Med. Genet. 35: 890-894.
4. De Cesare, D. et al. (1998) Proc. Natl. Acad.
Sci. 95: 12202-12207.
5. Joel, P. B. et al. (1998) Mol. Cell. Biol. 18:
1978-1984.
Storage Buffer TBS, 50% glycerol, 0.09% sodium azide
Gene Symbol RPS6KA1
Official Gene Full Name ribosomal protein S6 kinase, 90kDa, polypeptide 1
NCBI Gene Id 6195
Swissprot Id Q15418
Protein Accession # NP_002944.2
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express RPS6KA1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express RPS6KA1.
  1. What is the species homology for "p90 RSK1 Antibody (OASE00376)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Bovine".

  2. How long will it take to receive "p90 RSK1 Antibody (OASE00376)"?

    This item is available "Domestic: within 3-5 days delivery | International: 3-5 days".

  3. What buffer format is "p90 RSK1 Antibody (OASE00376)" provided in?

    This item is provided in "".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "p90 RSK1 Antibody (OASE00376)"?

    This target may also be called "" in publications.

  5. What is the shipping cost for "p90 RSK1 Antibody (OASE00376)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "p90 RSK1 Antibody (OASE00376)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "p90 RSK1 Antibody (OASE00376)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "p90 RSK1 Antibody (OASE00376)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "RPS6KA1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "RPS6KA1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "RPS6KA1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "RPS6KA1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "RPS6KA1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "RPS6KA1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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