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p53 Antibody (OADC00188)

50ug
$319.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid. Provided in PBS containing 0.05% azide and 0.05% ProClin 300.
Clonality:
Polyclonal
Host:
Rabbit
Conjugation:
Unconjugated
Application:
CHIP, WB
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Replacement Item:
This antibody may replace item sc-126 from Santa Cruz Biotechnology.
Purification:
Affinity purified
Concentration:
2.73 mg/mL
Datasheets/Manuals:
Printable datasheet for anti-TP53 (OADC00188) antibody
Preservative:
0.05% Sodium Azide and 0.05% ProClin 300.
Specificity:
Polyclonal antibody raised in rabbit against human p53 (tumor protein p53), using a KLH-conjugated synthetic peptide containing a sequence from the C-terminal part of the protein.
Application Info:
CHIP: 1 ug/CHIP
ELISA: 1:4,000
Western Blotting: 1:2,000
Gene Symbol:
TP53
Official Gene Full Name:
tumor protein p53
Alias Symbols:
P53, BCC7, LFS1, TRP53
NCBI Gene Id:
7157;
Protein Name:
cellular tumor antigen p53
Description of Target:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).
Swissprot Id:
P04637
Protein Accession #:
NP_000537.3
Nucleotide Accession #:
NM_000546.5
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express TP53.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express TP53.

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