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Catalog No: OADB00411
Size:1.0 mg
Price: $1,091.00
SKU
OADB00411
Availability: Domestic: within 1-2 weeks delivery ,International: within 1-2 weeks delivery
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p53 Antibody (OADB00411)

Datasheets/ManualsPrintable datasheet for anti-p53 (OADB00411) antibody
Product Info
Predicted Species ReactivityHuman
Product FormatLyophilized
ClonalityMonoclonal
CloneB-F34
IsotypeMouse IgG2b
HostMouse
Reconstitution and StorageStore at +2-8C for 12 months. For longer storage, freeze aliquots at -20C
PurificationIon exchange chromatography
Concentration1 mg/ml
SpecificityRecognises wild type and mutant p53, the epitope is within residues 18-30 of human p53
FormulationPhosphate-buffered saline.
Sterile-filtered through 0.22 um
Carrier and Preservative free
Storage BufferPhosphate-buffered saline.
Sterile-filtered through 0.22 um
Carrier and Preservative free
Biological ActivityThis Antibody can be used as Capture in a human p53 sandwich Immunoassay to detect human p53 in combination with biotinylated human p53 Detection Antibody
Gene Symbolp53
Gene Full Nametumor protein p53
Alias SymbolsP53, BCC7, LFS1, BMFS5, TRP53
NCBI Gene Id7157
Protein Namecellular tumor antigen p53
Description of TargetThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).
Uniprot IDP04637
Protein Accession #NP_000537.3
Nucleotide Accession #NM_000546.5
Molecular Weight44 kDa
  1. What is the species homology for "p53 Antibody (OADB00411)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "p53 Antibody (OADB00411)"?

    This item is available "Domestic: within 1-2 weeks delivery ,International: within 1-2 weeks delivery".

  3. What buffer format is "p53 Antibody (OADB00411)" provided in?

    This item is provided in "Lyophilized".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "p53 Antibody (OADB00411)"?

    This target may also be called "P53, BCC7, LFS1, BMFS5, TRP53" in publications.

  5. What is the shipping cost for "p53 Antibody (OADB00411)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "p53 Antibody (OADB00411)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "p53 Antibody (OADB00411)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "44 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "p53 Antibody (OADB00411)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "p53"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "p53"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "p53"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "p53"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "p53"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "p53"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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