Size:400ul
$340.00
Discontinued
SKU
OASE00374
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Conjugation Options

OASE00374-FITC Conjugated

OASE00374-HRP Conjugated

OASE00374-Biotin Conjugated

p33 ING1 Antibody (OASE00374)

Catalog#: OASE00374
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This product is Genway GWB-0X0005
More Information
Predicted Species Reactivity Human and Mouse
Clonality Polyclonal
Host Rabbit
Application WB, IF
Additional Information Background Info: Detects a ~33kDa protein corresponding to the molecular mass of p33 ING1 on SDS PAGE immunoblots.
:: Scientific Background: The p33ING1 protein encodes a 33-kD, 294-amino acid protein that displays the characteristics of a tumor suppressor gene. The p33ING1 protein is a regulator of cell cycle, senescence, and apoptosis. It can mediate growth arrest, anchor dependent growth and influence chemo sensitivity (1-4). It also has a proposed role as a growth regulator, which is consistent with its location in the nucleus (5).
It has been demonstrated that the ING1 gene has three exons and that four mRNA variants are transcribed from three different promoter regions (p33 ING1, p24 ING1, p27 ING1, p47 IG1) (6, 7). ING1 can possibly influence the above biological functions depending on which variant is expressed (1-4).
:: Certificate of Analysis: 0.25mg/mL was sufficient for detection of in lysates prepared from human melanoma cell lines by western blot analysis.
Reconstitution and Storage Store at -20C. Shipping in Blue Ice or 4C.
Replacement Item This antibody may replace item sc-373817 from Santa Cruz Biotechnology.
Immunogen Mouse p33 ING1 N-terminal peptide –KLH conjugates
Purification Rabbit immunoglobulin
Concentration 250ug/mL
Datasheets/Manuals Printable datasheet for OASE00374
Dilution 1ug/mL (WB)
Target Reference 1. Cheung, K.J., Jr. and Li, G. (2002) Int. J. Oncol. 21(6): 1361-1365.
2. Cheung, K.J., Jr. and Li, G. (2002) Exp. Cell
Res. 279(2): 291-28.
3. Cheung, K.J., Jr. and Li, G. (2002) Int. J.
Oncol. 20(6):1319-1322.
4. Cheung, K.J., Jr. and Li, G. (2001) Exp. Cell
Res. 268(1): 1-6.
5. Garkavtsev, I. et al. (1996). Nat Genet. 14
(4): 415-420.
6. Gunduz, M. et al. (2000). Cancer Res. 60
(12): 3143-6.
7. Jager, D. et al. (1999). Cancer Res. 59: 6197-
6204.
Storage Buffer TBS, 50% glycerol, 0.09% sodium azide
Gene Symbol Ing1
Official Gene Full Name inhibitor of growth family, member 1
NCBI Gene Id 26356
Swissprot Id Q9QXV3
Protein Accession # NP_036049.2
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express Ing1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express Ing1.
  1. What is the species homology for "p33 ING1 Antibody (OASE00374)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human and Mouse".

  2. How long will it take to receive "p33 ING1 Antibody (OASE00374)"?

    This item is available "Domestic: within 3-5 days delivery | International: 3-5 days".

  3. What buffer format is "p33 ING1 Antibody (OASE00374)" provided in?

    This item is provided in "".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "p33 ING1 Antibody (OASE00374)"?

    This target may also be called "" in publications.

  5. What is the shipping cost for "p33 ING1 Antibody (OASE00374)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "p33 ING1 Antibody (OASE00374)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "p33 ING1 Antibody (OASE00374)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "p33 ING1 Antibody (OASE00374)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "ING1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ING1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ING1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ING1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ING1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ING1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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