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- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for OAAB16425 |
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| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Clonality | Polyclonal |
| Isotype | Ig |
| Host | Rabbit |
| Application | DB |
| Additional Information | Precautions: p27Kip1 Antibody (Phospho T170) is for research use only and not for use in diagnostic or therapeutic procedures. |
| :: | Function: Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1- CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry |
| :: | Cellular Location: Nucleus. Cytoplasm. Endosome (By similarity). Note=Nuclear and cytoplasmic in quiescent cells. AKT- or RSK-mediated phosphorylation on Thr-198, binds 14-3-3, translocates to the cytoplasm and promotes cell cycle progression Mitogen-activated UHMK1 phosphorylation on Ser-10 also results in translocation to the cytoplasm and cell cycle progression Phosphorylation on Ser-10 facilitates nuclear export Tissue Location: Expressed in all tissues tested. Highest levels in skeletal muscle, lowest in liver and kidney |
| Reconstitution and Storage | Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | This p27Kip1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T170 of human p27Kip1. |
| Predicted Homology Based on Immunogen Sequence | Human |
| Concentration | Approximately 0.5mg/ml. Actual concentration varies with each lot. |
| Application Info | DB: 1:500 |
| Gene Symbol | CDKN1B |
|---|---|
| Alias Symbols | KIP1, MEN4, CDKN4, MEN1B, P27KIP1 |
| NCBI Gene Id | 1027 |
| Protein Name | Cyclin-dependent kinase inhibitor 1B |
| Description of Target | Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |
| Uniprot ID | P46527 |
| Protein Accession # | NP_004055.1 |
| Molecular Weight | 22073 Da |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "p27Kip1 Antibody (Phospho-Thr170) (OAAB16425)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "p27Kip1 Antibody (Phospho-Thr170) (OAAB16425)"?
This item is available "Domestic: within 1 week delivery | International: 1 week".
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What buffer format is "p27Kip1 Antibody (Phospho-Thr170) (OAAB16425)" provided in?
This item is provided in "Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "p27Kip1 Antibody (Phospho-Thr170) (OAAB16425)"?
This target may also be called "KIP1, MEN4, CDKN4, MEN1B, P27KIP1" in publications.
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What is the shipping cost for "p27Kip1 Antibody (Phospho-Thr170) (OAAB16425)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "p27Kip1 Antibody (Phospho-Thr170) (OAAB16425)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "p27Kip1 Antibody (Phospho-Thr170) (OAAB16425)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "22073 Da".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "p27Kip1 Antibody (Phospho-Thr170) (OAAB16425)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "CDKN1B"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "CDKN1B"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "CDKN1B"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "CDKN1B"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "CDKN1B"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "CDKN1B"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
