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Datasheets/Manuals | Printable datasheet for anti-ORF45 (OAEC04251) antibody |
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Product Format | Purified antibody in PBS containing 0.03% sodium azide |
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Clonality | Monoclonal |
Clone | 2D4A5 |
Isotype | IgG1 |
Host | Mouse |
Application | WB, IF |
Reconstitution and Storage | Store at 4C, for long term storage, store at -20C. |
Immunogen | Purified recombinant fragment of KSHV ORF45 expres sed in EColi |
Concentration | 1 mg/ml |
Application Info | WB: 1/500 - 1/2000 IF: 1/200 - 1/1000 ELISA: 1/10000 |
Gene Symbol | ORF45 |
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Gene Full Name | virion phosphoprotein |
NCBI Gene Id | 4961474 |
Description of Target | Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lym phoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. ORF45 protein encoded by an immediate-early gene in the KSHV genome is characterized as a phosphorylated protein, and it is localized in the cytoplasm of infected cells. Studies have shown that ORF45 Protein interacted with cellular IRF-7 and blocked virus -mediated phosphorylation and nuclear translocation of IRF-7. In consequence, ORF45 efficiently inhibited virus -induced production of type I IFN. Zhu et al (2003) reported that the ORF45 Protein was associated with purified virions |
Uniprot ID | F5HDE4 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "ORF45 Antibody (OAEC04251)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "".
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How long will it take to receive "ORF45 Antibody (OAEC04251)"?
This item is available "Domestic: within 2-3 weeks delivery | International: 2-3 weeks".
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What buffer format is "ORF45 Antibody (OAEC04251)" provided in?
This item is provided in "Purified antibody in PBS containing 0.03% sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "ORF45 Antibody (OAEC04251)"?
This target may also be called "" in publications.
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What is the shipping cost for "ORF45 Antibody (OAEC04251)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "ORF45 Antibody (OAEC04251)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "ORF45 Antibody (OAEC04251)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "ORF45 Antibody (OAEC04251)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ORF45"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ORF45"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ORF45"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ORF45"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ORF45"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ORF45"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.