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Catalog No: OAAL00227
Size:100UG
Price: $420.00
SKU
OAAL00227
Availability: Domestic: within 2-3 week delivery | International: 2-3 weeks
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Datasheets/ManualsPrintable datasheet for ORC1L Antibody (OAAL00227)
Product Info
Predicted Species ReactivityHuman, Mouse
Product FormatLiquid
ClonalityMonoclonal
Clone3H1
IsotypeIgG2b Kappa
HostMouse
ApplicationEnzyme-linked immunosorbent assay|Immunohistochemistry-Paraffin
Reconstitution and StorageStore at -20C or lower. Aliquot to avoid repeated freezing and thawing.
ImmunogenORC1L (AAH11539, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Peptide SequenceMAHYPTRLKTRKTYSWVGRPLLDRKLHYQTYREMCVKTEGCSTEIHIQIGQFVLIEGDDDENPYVAKLLELFEDDSDPPPKKRARVQWFVRFCEVPACKRHLLGRKPGAQ
FormulationIn 1x PBS, pH 7.4
Gene SymbolORC1
Gene Full Nameorigin recognition complex subunit 1
Alias SymbolsHSORC1;ORC1L;origin recognition complex subunit 1;origin recognition complex, subunit 1 homolog;PARC1;replication control protein 1.
NCBI Gene Id4998
Protein NameHomo sapiens origin recognition complex, subunit 1-like (yeast), mRNA (cDNA clone MGC:9175 IMAGE:3870637), complete cds|Origin recognition complex, subunit 1-like (yeast) [Homo sapiens]
Description of TargetThe origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is the largest subunit of the ORC complex. While other ORC subunits are stable throughout the cell cycle, the levels of this protein vary during the cell cycle, which has been shown to be controlled by ubiquitin-mediated proteolysis after initiation of DNA replication. This protein is found to be selectively phosphorylated during mitosis. It is also reported to interact with MYST histone acetyltransferase 2 (MyST2/HBO1), a protein involved in control of transcription silencing. [provided by RefSeq
Protein Accession #https://www.ncbi.nlm.nih.gov/protein/AAH11539
Nucleotide Accession #https://www.ncbi.nlm.nih.gov/nuccore/BC011539
  1. What is the species homology for "ORC1L Antibody (OAAL00227)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".

  2. How long will it take to receive "ORC1L Antibody (OAAL00227)"?

    This item is available "Domestic: within 2-3 week delivery | International: 2-3 weeks".

  3. What buffer format is "ORC1L Antibody (OAAL00227)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ORC1L Antibody (OAAL00227)"?

    This target may also be called "HSORC1;ORC1L;origin recognition complex subunit 1;origin recognition complex, subunit 1 homolog;PARC1;replication control protein 1." in publications.

  5. What is the shipping cost for "ORC1L Antibody (OAAL00227)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ORC1L Antibody (OAAL00227)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ORC1L Antibody (OAAL00227)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ORC1L Antibody (OAAL00227)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ORC1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ORC1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ORC1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ORC1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ORC1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ORC1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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