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Catalog No: OAPB01360
Size:100UG
Price: $536.00
SKU
OAPB01360
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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ORAI1 Antibody (OAPB01360)

Datasheets/ManualsPrintable datasheet for ORAI1 Antibody (OAPB01360) (OAPB01360)
Product Info
Predicted Species ReactivityHuman|Mouse|Rat
Product FormatLiquid. ORAI1 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
ClonalityMonoclonal
HostORAI1 monoclonal antibody was raised in mouse.
Please use anti-mouse secondary antibodies.
ConjugationUnconjugated
ApplicationEnzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Additional InformationHuman Ovary Tissue Lysate (OCPB00134)
::Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and StorageORAI1 monoclonal antibody can be stored at 4C, stable for one year.
ImmunogenMouse monoclonal ORAI1 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human ORAI1.
PurificationProtein A Purified
Predicted Homology Based on Immunogen SequenceHuman; Mouse; Rat
Concentration1 mg/ml
Application InfoORAI1 antibody can be used for detection of ORAI1 by Western blot at 1 – 2 ug/mL. (Optimal dilution should be determined by user)
ReferenceLewis RS. Calcium signaling mechanisms in T lymphocytes. Annu. Rev. Immunol. 2001; 19:497-521.;Feske S, Gwack Y, Prakriya M, et al. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 2006; 441:179-85.;Soboloff J, Spassova MA, Dziadek MA, et al. Calcium signals mediated by STIM and Orai proteins – a new paradigm in inter-organelle communication. Biochim. Biophys. Acta. 2006; 1763:1161-8.;
Gene SymbolORAI1
Gene Full NameORAI calcium release-activated calcium modulator 1
Alias Symbolscalcium release-activated calcium channel protein 1;calcium release-activated calcium modulator 1;CRACM1;IMD9;ORAT1;protein orai-1;TAM2;TMEM142A;transmembrane protein 142A.
NCBI Gene Id84876
Protein NameCalcium release-activated calcium channel protein 1
Description of TargetCa(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1 (PubMed:16582901, PubMed:16645049, PubMed:16733527, PubMed:16766533, PubMed:16807233, PubMed:19249086, PubMed:23307288, PubMed:24351972, PubMed:24591628, PubMed:28219928). CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT (PubMed:16582901).
Uniprot IDQ96D31
Molecular WeightPredicted: 33 kDa Observed: 56 kDa
  1. What is the species homology for "ORAI1 Antibody (OAPB01360)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".

  2. How long will it take to receive "ORAI1 Antibody (OAPB01360)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "ORAI1 Antibody (OAPB01360)" provided in?

    This item is provided in "Liquid. ORAI1 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ORAI1 Antibody (OAPB01360)"?

    This target may also be called "calcium release-activated calcium channel protein 1;calcium release-activated calcium modulator 1;CRACM1;IMD9;ORAT1;protein orai-1;TAM2;TMEM142A;transmembrane protein 142A." in publications.

  5. What is the shipping cost for "ORAI1 Antibody (OAPB01360)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ORAI1 Antibody (OAPB01360)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ORAI1 Antibody (OAPB01360)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "Predicted: 33 kDa Observed: 56 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ORAI1 Antibody (OAPB01360)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ORAI1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ORAI1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ORAI1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ORAI1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ORAI1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ORAI1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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