Size:100 ul
Special Price $229.00 Regular Price $319.00
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ARP49154_P050
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Conjugation Options

ARP49154_P050-FITC Conjugated

ARP49154_P050-HRP Conjugated

ARP49154_P050-Biotin Conjugated

OGT Antibody - N-terminal region (ARP49154_P050)

Catalog#: ARP49154_P050
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application IHC, WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-22625 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human OGT
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Complete computational species homology data Anti-OGT (ARP49154_P050)
Peptide Sequence Synthetic peptide located within the following region: ASSVGNVADSTEPTKRMLSFQGLAELAHREYQAGDFEAAERHCMQLWRQE
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-OGT (ARP49154_P050) antibody is Catalog # AAP49154 (Previous Catalog # AAPY02354)
Datasheets/Manuals Printable datasheet for anti-OGT (ARP49154_P050) antibody
Sample Type Confirmation

OGT is strongly supported by BioGPS gene expression data to be expressed in 721_B

Target Reference Taylor,R.P., (2008) J. Biol. Chem. 283 (10), 6050-6057
Gene Symbol OGT
Official Gene Full Name O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
Alias Symbols FLJ23071, HRNT1, MGC22921, O-GLCNAC
NCBI Gene Id 8473
Protein Name UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
Description of Target OGT catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains nine tetratricopeptide repeats and a putative bipartite nuclear localization signal. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains nine tetratricopeptide repeats and a putative bipartite nuclear localization signal. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Swissprot Id O15294
Protein Accession # NP_858058
Nucleotide Accession # NM_181672
Protein Size (# AA) 1046
Molecular Weight 117kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express OGT.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express OGT.
Protein Interactions FBXW11; HUWE1; UBC; PSG1; PHC3; NUP62CL; TET2; SUMO1; NEDD8; WWOX; BAP1; P3H1; RPRD1B; PPME1; LAP3; DBNL; HSPBP1; GPN1; WDR4; ACTR2; TOM1L1; ZPR1; SURF2; LPP; AGFG1; ALAD; C14orf142; UBL4A; FOXO4; HCFC1; SMURF1; Hoxa1; Nfatc1; Nup62; RELA; PPP1CB; PPP1CA;
  1. What is the species homology for "OGT Antibody - N-terminal region (ARP49154_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish".

  2. How long will it take to receive "OGT Antibody - N-terminal region (ARP49154_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "OGT Antibody - N-terminal region (ARP49154_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "OGT Antibody - N-terminal region (ARP49154_P050)"?

    This target may also be called "FLJ23071, HRNT1, MGC22921, O-GLCNAC" in publications.

  5. What is the shipping cost for "OGT Antibody - N-terminal region (ARP49154_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "OGT Antibody - N-terminal region (ARP49154_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "OGT Antibody - N-terminal region (ARP49154_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "117kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "OGT Antibody - N-terminal region (ARP49154_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "OGT"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "OGT"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "OGT"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "OGT"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "OGT"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "OGT"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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