OGDH Recombinant Protein (OPCD05900)

Catalog No: OPCD05900

OGDH Recombinant Protein (OPCD05900) using SDS-PAGE

OGDH Recombinant Protein (OPCD05900) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Ala256-Lys582
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: OGDH
• Gene Full Name: oxoglutarate dehydrogenase
• Alias Symbols: 2-oxoglutarate dehydrogenase complex component E1;2-oxoglutarate dehydrogenase, mitochondrial;AKGDH;Alpha-ketoglutarate dehydrogenase;E1k;KGD1;OGDC;OGDC-E1;OGDH2;oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide);oxoglutarate decarboxylase;oxoglutarate dehydrogenase (succinyl-transferring);testicular tissue protein Li 131.
• NCBI Gene Id: 4967
• Protein Name: 2-oxoglutarate dehydrogenase, mitochondrial
• Description of Target: 2-oxoglutarate dehydrogenase (E1) component of the 2-oxoglutarate dehydrogenase complex, which mediates the decarboxylation of alpha-ketoglutarate (PubMed:24495017). The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) (PubMed:24495017). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion (PubMed:29211711). A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A (PubMed:29211711).
• Uniprot ID: Q02218
• Protein Accession #: NP_001003941.1
• Nucleotide Accession #: NM_001003941.2
• Protein Size (# AA): Ala256~Lys582
• Molecular Weight: 41kDa