OFD1 Antibody (OACA10378)

Catalog No: OACA10378

Immunofluorescent analysis of HepG2 cells at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Immunohistochemistry of paraffin-embedded human adrenal gland tissue at dilution of 1:100

Western Blot
Positive WB detected in: Mouse skeletal muscle tissue
All lanes: OFD1 antibody at 2ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/5,0000 dilution
Predicted band size: 117,43,112 KDa
Observed band size: 117 KDa

Western Blot
Positive WB detected in: Mouse skeletal muscle tissue
All lanes: OFD1 antibody at 2ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/5,0000 dilution
Predicted band size: 117,43,112 KDa
Observed band size: 117 KDa

Immunohistochemistry of paraffin-embedded human adrenal gland tissue at dilution of 1:100

Immunofluorescent analysis of HepG2 cells at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Product Info

• Predicted Species Reactivity: Human|Mouse
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
• Reconstitution and Storage: -20°C or -80°C
• Immunogen: Recombinant Human Oral-facial-digital syndrome 1 protein (598-771AA)
• Purification: Protein G Purified
• Preservative: 0.03% Proclin 300
• Formulation: 50% Glycerol, 0.01M PBS, pH 7.4
• Purity: >95%

Target Info

• Gene Symbol: OFD1
• Gene Full Name: OFD1 centriole and centriolar satellite protein
• Alias Symbols: 71-7A;CXorf5;JBTS10;Joubert syndrome type 10;oral-facial-digital syndrome 1 protein;protein 71-7A;RP23;SGBS2.
• NCBI Gene Id: 8481
• Protein Name: Oral-facial-digital syndrome 1 protein
• Description of Target: Component of the centrioles controlling mother and daughter centrioles length. Recruits to the centriole IFT88 and centriole distal appendage-specific proteins including CEP164. Involved in the biogenesis of the cilium, a centriole-associated function. The cilium is a cell surface projection found in many vertebrate cells required to transduce signals important for development and tissue homeostasis. Plays an important role in development by regulating Wnt signaling and the specification of the left-right axis. Only OFD1 localized at the centriolar satellites is removed by autophagy, which is an important step in the ciliogenesis regulation (By similarity).
• Uniprot ID: O75665
• Protein Accession #: NP_001317138
• Nucleotide Accession #: NM_001330209