ODC Antibody (OAAD00184)

Catalog No: OAAD00184

Size:100 ug

Western blot At 4?g/ml with the appropriate system to detect ODC in cells and tissues.
Immunohistochemistry(P) At 8?g/ml to detect ODC in formalin fixed and paraffin embedded tissues.
Other applications have not been tested.
Optimal dilutions should be determined by end user.

Product Info

• Predicted Species Reactivity: Human
• Clonality: Monoclonal
• Clone: ODC-22
• Isotype: IgG2b
• Host: Mouse
• Application: WB, IHC, IP
• Reconstitution and Storage: At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for longer time.
• Immunogen: Recombinant mouse ornithine decarboxylase.
• Purification: Purified by the goat anti-mouse IgG Affinity chromatography.
• Specificity: Human.
  No cross reactivity with other proteins.
• Formulation: Lyophilized from 1.2% sodium acetate, with 2mg BSA and 0.01mg NaN3 as preservative.
• Application Info: Western blot At 4ug/ml with the appropriate system to detect ODC in cells and tissues.
  Immunohistochemistry(P) At 8ug/ml to detect ODC in formalin fixed and paraffin embedded tissues.
  Other applications have not been tested.
  Optimal dilutions should be determined by end user.
• Storage Buffer: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.
• Reference: 1. Cox, D. R.; Trouillot, T.; Ashley, P. L.; Brabant, M.; Coffino, P. : A functional mouse ornithine decarboxylase gene (Odc) maps to chromosome 12: further evidence of homoeology between mouse chromosome 12 and the short arm of human chromosome 2. Cytogenet. Cell Genet. 48: 92-94, 1988.
  2. Hickok, N. J.; Seppanen, P. J.; Gunsalus, G. L.; Janne, O. A. : Complete amino acid sequence of human ornithine decarboxylase deduced from complementary DNA. DNA 6: 179-187, 1987.

Target Info

• Gene Symbol: ODC1
• Alias Symbols: ODC, BABS, NEDBA, NEDBIA
• NCBI Gene Id: 4953
• Protein Name: Ornithine decarboxylase
• Description of Target: Ornithine decarboxylase (ODC), the first enzyme in polyamine synthesis, is a transcriptional target of MYC and a modifier of APC -dependent tumorigenesis. It is located to 2p25. There is considerable genetic homology between a region of mouse chromosome 12 and the distal short arm of human chromosome 2. Complete amino acid sequence of human ornithine decarboxylase deduced from complementary DNA.
• Uniprot ID: P11926