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Catalog No: OAAB07793
Size:400ul
Price: $438.00
SKU
OAAB07793
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.
Datasheets/ManualsPrintable datasheet for OAAB07793
Product Info
Predicted Species ReactivityHuman
Product FormatLiquid PBS with 0.09% (W/V) sodium azide.
ClonalityPolyclonal
IsotypeIg
HostRabbit
ApplicationWB, IHC-P
::Function: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Cellular Location: Cytoplasm. Nucleus. Note=Expressed in a diffuse and slightly punctuate pattern.
Tissue Location: Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis OCT3/4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-297 amino acids from human OCT3/4.
PurificationThis antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration2 mg/ml
Application InfoWB: 1:1000
IHC-P: 1:50~100
Gene SymbolPOU5F1
Alias SymbolsOCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4
NCBI Gene Id5460
Protein NamePOU domain, class 5, transcription factor 1
Description of TargetThis gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
Uniprot IDQ01860
Protein Accession #NP_002692.2
Molecular Weight39 kDa
  1. What is the species homology for "OCT3/4 Antibody (Phospho-C279) (OAAB07793)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "OCT3/4 Antibody (Phospho-C279) (OAAB07793)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "OCT3/4 Antibody (Phospho-C279) (OAAB07793)" provided in?

    This item is provided in "Liquid PBS with 0.09% (W/V) sodium azide. ".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "OCT3/4 Antibody (Phospho-C279) (OAAB07793)"?

    This target may also be called "OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4" in publications.

  5. What is the shipping cost for "OCT3/4 Antibody (Phospho-C279) (OAAB07793)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "OCT3/4 Antibody (Phospho-C279) (OAAB07793)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "OCT3/4 Antibody (Phospho-C279) (OAAB07793)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "39 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "OCT3/4 Antibody (Phospho-C279) (OAAB07793)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "POU5F1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "POU5F1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "POU5F1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "POU5F1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "POU5F1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "POU5F1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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