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Catalog No: OPCD05834
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OPCD05834
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Datasheets/ManualsPrintable datasheet for NTRK3 Recombinant Protein (OPCD05834)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Cys32-Thr429
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 90%
SourceE.coli
TagN-terminal His Tag
Gene SymbolNTRK3
Gene Full Nameneurotrophic receptor tyrosine kinase 3
Alias SymbolsETS related protein-neurotrophic receptor tyrosine kinase fusion protein;ETV6-NTRK3 fusion;gp145(trkC);GP145-TrkC;Neurotrophic tyrosine kinase receptor type 3;neurotrophic tyrosine kinase, receptor, type 3;NT-3 growth factor receptor;TRKC;TrkC tyrosine kinase;tyrosine kinase receptor C.
NCBI Gene Id4916
Protein NameNT-3 growth factor receptor
Description of TargetReceptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.
Uniprot IDQ16288
Protein Accession #NP_001012338.1
Nucleotide Accession #NM_001012338.2
Protein Size (# AA)Cys32~Thr429
Molecular Weight48.4kDa
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