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NTRK2 Antibody - C-terminal region (ARP51316_P050)

100 ul
$289.00
In Stock
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Conjugation Options

ARP51316_P050-FITC Conjugated

ARP51316_P050-HRP Conjugated

ARP51316_P050-Biotin Conjugated

Tested Species Reactivity:
Human, Mouse
Predicted Species Reactivity:
Cow, Horse, Human, Rabbit, Rat
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality:
Polyclonal
Host:
Rabbit
Application:
IF, WB, IHC
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Gene Symbol:
NTRK2
Official Gene Full Name:
Neurotrophic tyrosine kinase, receptor, type 2
NCBI Gene Id:
4915
Protein Name:
BDNF/NT-3 growth factors receptor
Swissprot Id:
Q8WXJ5
Protein Accession #:
NP_001018075
Nucleotide Accession #:
NM_001018065
Alias Symbols:
GP145-TrkB, TRKB, trk-B
Replacement Item:
This antibody may replace item sc-113925 from Santa Cruz Biotechnology.
Description of Target:
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders.
Protein Size (# AA):
553
Molecular Weight:
57kDa
Purification:
Affinity Purified
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express NTRK2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express NTRK2.
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human NTRK2
Predicted Homology Based on Immunogen Sequence:
Cow: 88%; Horse: 100%; Human: 100%; Rabbit: 100%; Rat: 100%
Complete computational species homology data:
Anti-NTRK2 (ARP51316_P050)
Peptide Sequence:
Synthetic peptide located within the following region: DFSWFGFGKVKSRQGVGPASVISNDDDSASPLHHISNGSNTPSSSEGGPD
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
TNK2; RANBP9; POLR2G; HSP90AA1; AP1B1; NMNAT1; UBC; NTF4; Nedd4; SHC2; KIDINS220; DOK5; SH2B2; SH2B1; SHC3; RASGRF1; UBB; FRS3; GIPC1; NCK2; DYNLL1; SQSTM1; SHC1; NCK1; NTRK2; PTPN1; PTPN11; PLCG1; NTF3; NGFR; FYN; BDNF; TRAF6; PIK3R1; FRS2;
Blocking Peptide:
For anti-NTRK2 (ARP51316_P050) antibody is Catalog # AAP51316 (Previous Catalog # AAPP46572)
Datasheets/Manuals:
Printable datasheet for anti-NTRK2 (ARP51316_P050) antibody

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