- Toll Free: 888-880-0001
- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for NR5A2 Antibody (OACA10372) (OACA10372) |
|---|
| Predicted Species Reactivity | Human|Mouse |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot |
| Reconstitution and Storage | -20°C or -80°C |
| Immunogen | Recombinant Human Nuclear receptor subfamily 5 group A member 2 protein (182-291AA) |
| Purification | Protein G Purified |
| Preservative | 0.03% Proclin 300 |
| Formulation | 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purity | >95% |
| Gene Symbol | NR5A2 |
|---|---|
| Gene Full Name | nuclear receptor subfamily 5 group A member 2 |
| Alias Symbols | Alpha-1-fetoprotein transcription factor;B1-binding factor;b1-binding factor, hepatocyte transcription factor which activates enhancer II of hepatitis B virus;B1F;B1F2;CPF;CYP7A promoter-binding factor;fetoprotein-alpha 1 (AFP) transcription factor;FTF;FTZ-F1;FTZ-F1beta;hB1F-2;Hepatocytic transcription factor;hepatocytic transcription factor hB1F-3;liver nuclear receptor homolog-1 variant 2;Liver receptor homolog 1;LRH1;LRH-1;nuclear receptor subfamily 5 group A member 2. |
| NCBI Gene Id | 2494 |
| Protein Name | Nuclear receptor subfamily 5 group A member 2 |
| Description of Target | Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis. Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism. Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex (PubMed:20159957). Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development. |
| Uniprot ID | O00482 |
| Protein Accession # | NP_001263393 |
| Nucleotide Accession # | NM_001276464 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
-
See our General FAQ page.
-
What is the species homology for "NR5A2 Antibody (OACA10372)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".
-
How long will it take to receive "NR5A2 Antibody (OACA10372)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
-
What buffer format is "NR5A2 Antibody (OACA10372)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "NR5A2 Antibody (OACA10372)"?
This target may also be called "Alpha-1-fetoprotein transcription factor;B1-binding factor;b1-binding factor, hepatocyte transcription factor which activates enhancer II of hepatitis B virus;B1F;B1F2;CPF;CYP7A promoter-binding factor;fetoprotein-alpha 1 (AFP) transcription factor;FTF;FTZ-F1;FTZ-F1beta;hB1F-2;Hepatocytic transcription factor;hepatocytic transcription factor hB1F-3;liver nuclear receptor homolog-1 variant 2;Liver receptor homolog 1;LRH1;LRH-1;nuclear receptor subfamily 5 group A member 2." in publications.
-
What is the shipping cost for "NR5A2 Antibody (OACA10372)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
-
What is the guarantee for "NR5A2 Antibody (OACA10372)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
-
Can I get bulk pricing for "NR5A2 Antibody (OACA10372)"?
You can get bulk pricing for this item by going here.
-
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "NR5A2 Antibody (OACA10372)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
-
What are positive controls for "NR5A2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What are negative controls for "NR5A2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What other proteins interact with "NR5A2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
-
What biological processes are associated with "NR5A2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
-
What cellular components are associated with "NR5A2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
-
What protein functions are associated with "NR5A2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
