NR3C2 Recombinant Protein (OPCD05389)

Catalog No: OPCD05389

NR3C2 Recombinant Protein (OPCD05389) using SDS-PAGE

NR3C2 Recombinant Protein (OPCD05389) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Val739-Lys984
  Subcellular Location: Membrane, Nucleus, Cytoplasm, Endoplasmic reticulum lumen
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 90%
• Source: E.coli
• Tag: N-terminal His and GST Tag

Target Info

• Gene Symbol: NR3C2
• Gene Full Name: nuclear receptor subfamily 3 group C member 2
• Alias Symbols: aldosterone receptor;MCR;mineralocorticoid receptor;mineralocorticoid receptor 1;mineralocorticoid receptor 2;mineralocorticoid receptor delta;MLR;MR;NR3C2VIT;Nuclear receptor subfamily 3 group C member 2;nuclear receptor subfamily 3, group C, member 2 variant 3.
• NCBI Gene Id: 4306
• Protein Name: Mineralocorticoid receptor
• Description of Target: Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
• Uniprot ID: P08235
• Protein Accession #: NP_000892.2
• Nucleotide Accession #: NM_000901.4
• Protein Size (# AA): Val739~Lys984
• Molecular Weight: 59kDa