NR3C2 Antibody - C-terminal region : HRP (P100726_P050-HRP)

Catalog No: P100726_P050-HRP

Size:100ul

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Horse
• Product Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: HRP: Horseradish Peroxidase
• Application: WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NR3C2
• Predicted Homology Based on Immunogen Sequence: Cow: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: VSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-NR3C2 (P100726_P050-HRP) antibody is Catalog # AAP31009 (Previous Catalog # AAPP01742)

Target Info

• Gene Symbol: NR3C2
• Gene Full Name: Nuclear receptor subfamily 3, group C, member 2
• Alias Symbols: MR, MCR, MLR, NR3C2VIT
• NCBI Gene Id: 4306
• Protein Name: Mineralocorticoid receptor Ensembl ENSP00000423510
• Description of Target: NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
• Uniprot ID: B0ZBF5
• Protein Accession #: NP_001159576
• Nucleotide Accession #: NM_001166104
• Protein Size (# AA): 867
• Molecular Weight: 94kDa
• Protein Interactions: RABAC1; RXRA; HSP90AA1; ACSL1; UBC; SRC; PPP5C; PPID; FKBP5; FKBP4; STUB1; AIP; TRIM24; NRIP1; DNAJC7; CAND1; SUMO1; UBE2I; EIF3I; PROX1; PIAS1; PIAS3; HSPA4; PTGES3; AR; NR3C1; ACTA1; ACTG1;