- Toll Free: 888-880-0001
- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
Datasheets/Manuals | Printable datasheet for NR3C1 Antibody (Phospho-Ser203) (OAAF00410) |
---|
Predicted Species Reactivity | Human|Mouse |
---|---|
Product Format | Liquid |
Clonality | Polyclonal |
Host | Rabbit |
Application | Enzyme-linked immunosorbent assay|Western blot |
Reconstitution and Storage | -20°C |
Immunogen | The antiserum was produced against synthesized peptide derived from human GR around the phosphorylation site of Ser203. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Specificity | GR (Phospho-Ser203) antibody detects endogenous levels of GR only when phosphorylated at serine 203. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Dilution | The optimal working dilution should be determined by the end user. |
Application Info | WB: 1:500~1:3000; ELISA: 1:10000 |
Reference | Hollenberg S.M., Nature 318:635-641(1985). Encio I.J., J. Biol. Chem. 266:7182-7188(1991). Munroe D.G., Submitted (SEP-1993) to the EMBL/GenBank/DDBJ databases. |
Gene Symbol | NR3C1 |
---|---|
Gene Full Name | nuclear receptor subfamily 3 group C member 1 |
Alias Symbols | GCCR;GCR;GCRST;glucocorticoid nuclear receptor variant 1;glucocorticoid receptor;GR;GRL;Nuclear receptor subfamily 3 group C member 1;nuclear receptor subfamily 3 group C member 1 variant hGR-B(54);nuclear receptor subfamily 3 group C member 1 variant hGR-B(77);nuclear receptor subfamily 3 group C member 1 variant hGR-B(93);nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor). |
NCBI Gene Id | 2908 |
Protein Name | Glucocorticoid receptor |
Description of Target | Receptor for glucocorticoids (GC) (PubMed:27120390). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling (PubMed:9590696). Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay (PubMed:25775514). Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth (By similarity). |
Uniprot ID | P04150 |
Protein Accession # | NP_000167.1 |
Molecular Weight | 85 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
-
See our General FAQ page.
-
What is the species homology for "NR3C1 Antibody (Phospho-Ser203) (OAAF00410)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".
-
How long will it take to receive "NR3C1 Antibody (Phospho-Ser203) (OAAF00410)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
-
What buffer format is "NR3C1 Antibody (Phospho-Ser203) (OAAF00410)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "NR3C1 Antibody (Phospho-Ser203) (OAAF00410)"?
This target may also be called "GCCR;GCR;GCRST;glucocorticoid nuclear receptor variant 1;glucocorticoid receptor;GR;GRL;Nuclear receptor subfamily 3 group C member 1;nuclear receptor subfamily 3 group C member 1 variant hGR-B(54);nuclear receptor subfamily 3 group C member 1 variant hGR-B(77);nuclear receptor subfamily 3 group C member 1 variant hGR-B(93);nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)." in publications.
-
What is the shipping cost for "NR3C1 Antibody (Phospho-Ser203) (OAAF00410)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
-
What is the guarantee for "NR3C1 Antibody (Phospho-Ser203) (OAAF00410)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
-
Can I get bulk pricing for "NR3C1 Antibody (Phospho-Ser203) (OAAF00410)"?
You can get bulk pricing for this item by going here.
-
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "85 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "NR3C1 Antibody (Phospho-Ser203) (OAAF00410)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
-
What are positive controls for "NR3C1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What are negative controls for "NR3C1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
-
What other proteins interact with "NR3C1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
-
What biological processes are associated with "NR3C1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
-
What cellular components are associated with "NR3C1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
-
What protein functions are associated with "NR3C1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.