Size:50ug
$319.00
In Stock
SKU
OADC00056
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More Information
Predicted Species Reactivity Human
Product Format Liquid. Provided in PBS containing 0.05% azide and 0.1% BSA; purified by ammonium sulphate precipitation followed by dialysis.
Clonality Monoclonal
Isotype IgG2b kappa
Host Mouse
Conjugation Unconjugated
Application CHIP, WB, GS, IHC, FC, IP
Reconstitution and Storage Store at -20C. Avoid repeated freeze/thaw cycles.
Replacement Item This antibody may replace item sc-12763 from Santa Cruz Biotechnology.
Purification Protein A/G purified
Predicted Homology Based on Immunogen Sequence Rat
Concentration 1 mg/mL
Datasheets/Manuals Printable datasheet for anti-NR3C1 (OADC00056) antibody
Preservative 0.05% Sodium Azide
Specificity Mouse monoclonal antibody raised against POLR2A
Application Info CHIP: 5 ug/CHIP
ELISA: 0.5 ug/ml
Western Blotting: 1 ug/ml
Gel Supershift 5 ug/ml
Immunochemistry 2.5 ug/ml
Flow Cytometry: 0.5 ug/ml
Immunoprecipitation: 5 ug per IP
Gene Symbol NR3C1
Official Gene Full Name nuclear receptor subfamily 3 group C member 1
Alias Symbols GR, GCR, GRL, GCCR, GCRST
NCBI Gene Id 2908;
Protein Name glucocorticoid receptor
Description of Target This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175).
Swissprot Id P04150
Protein Accession # NP_000167.1
Nucleotide Accession # NM_000176.2
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express NR3C1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express NR3C1.
  1. What is the species homology for "NR3C1 Antibody (OADC00056)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "NR3C1 Antibody (OADC00056)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "NR3C1 Antibody (OADC00056)" provided in?

    This item is provided in "Liquid. Provided in PBS containing 0.05% azide and 0.1% BSA; purified by ammonium sulphate precipitation followed by dialysis.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "NR3C1 Antibody (OADC00056)"?

    This target may also be called "GR, GCR, GRL, GCCR, GCRST" in publications.

  5. What is the shipping cost for "NR3C1 Antibody (OADC00056)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "NR3C1 Antibody (OADC00056)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "NR3C1 Antibody (OADC00056)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "NR3C1 Antibody (OADC00056)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "NR3C1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "NR3C1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "NR3C1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "NR3C1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "NR3C1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "NR3C1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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