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- $55: Antibody & Protein in US
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Datasheets/Manuals | Printable datasheet for NR2F6 Antibody (OAAF02133) |
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Predicted Species Reactivity | Human|Mouse|Rat |
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Product Format | Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Application | Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot |
Reconstitution and Storage | -20°C |
Immunogen | The antiserum was produced against synthesized peptide derived from human NR2F6. |
Purification | The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen. |
Concentration | 1 mg/ml |
Specificity | NR2F6 antibody detects endogenous levels of total NR2F6 protein. |
Dilution | The optimal working dilution should be determined by the end user. |
Application Info | WB: 1:500~1000 IHC: 1:50~100 IF: 1:100~500 ELISA: 1:20000 Optimal dilutions should be determined by the end user. |
Gene Symbol | NR2F6 |
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Gene Full Name | nuclear receptor subfamily 2 group F member 6 |
Alias Symbols | EAR2;EAR-2;ERBAL2;ERBA-related gene-2;nuclear receptor subfamily 2 group F member 6;nuclear receptor V-erbA-related;v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 2;V-erbA-related protein 2. |
NCBI Gene Id | 2063 |
Protein Name | Nuclear receptor subfamily 2 group F member 6 |
Description of Target | Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type-specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4(+) T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. Involved in development of forebrain circadian clock; is required early in the development of the locus coeruleus (LC). |
Uniprot ID | P10588 |
Protein Accession # | NP_005225.2 |
Molecular Weight | 42 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "NR2F6 Antibody (OAAF02133)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".
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How long will it take to receive "NR2F6 Antibody (OAAF02133)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "NR2F6 Antibody (OAAF02133)" provided in?
This item is provided in "Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "NR2F6 Antibody (OAAF02133)"?
This target may also be called "EAR2;EAR-2;ERBAL2;ERBA-related gene-2;nuclear receptor subfamily 2 group F member 6;nuclear receptor V-erbA-related;v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 2;V-erbA-related protein 2." in publications.
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What is the shipping cost for "NR2F6 Antibody (OAAF02133)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "NR2F6 Antibody (OAAF02133)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "NR2F6 Antibody (OAAF02133)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "42 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "NR2F6 Antibody (OAAF02133)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "NR2F6"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "NR2F6"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "NR2F6"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "NR2F6"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "NR2F6"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "NR2F6"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.