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Catalog No: OASE00185-HRP
Size:100ug
Price: $429.00
SKU
OASE00185-HRP
Availability: Domestic: within 3-5 days delivery | International: 3-5 days
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NR2B Antibody : HRP (OASE00185-HRP)

Datasheets/ManualsPrintable datasheet for OASE00185-HRP
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
ClonalityMonoclonal
CloneS59-36
IsotypeIgG2b
HostMouse
ConjugationHRP: Horseradish Peroxidase
ApplicationWB, IHC, IP
Additional InformationBackground Info: Detects ~166kDa. No cross-reactivity against NR2A
::Scientific Background: NR2B containing receptors have been implicated in synaptic plasticity, memory formation and pain modulation (3). Studies suggest that the NR2B subunit of glutamate receptors may be potential targets for relieving pain; NR2B may be a probable target for anti-nociceptive drugs, and may also be useful as analgesics (4).
::Certificate of Analysis: 1ug/mL was sufficient for detection of NR2B in 10ug of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenFusion protein amino acids 20-271 (extracellular N-terminus) of rat NR2B, accession number QOO960
PurificationProtein G Purified
Concentration0.6-0.7 mg/ml
Dilution1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF)
Storage BufferPBS pH7.4, 50% glycerol
Reference1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA.
2. www.iochannels.org
3. Zhuo M. (2009) Mol Brain. 2(1): 4
4. Gurwitz D, and Weizman A. (2002) Drug Discovery Today, 7(7): 403-406.
Gene SymbolGrin2b
Gene Full Nameglutamate receptor, ionotropic, N-methyl D-aspartate 2B
Alias SymbolsGluN2B
NCBI Gene Id24410
Uniprot IDQ00960
Protein Accession #NP_036706.1
  1. What is the species homology for "NR2B Antibody : HRP (OASE00185-HRP)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "NR2B Antibody : HRP (OASE00185-HRP)"?

    This item is available "Domestic: within 3-5 days delivery | International: 3-5 days".

  3. What buffer format is "NR2B Antibody : HRP (OASE00185-HRP)" provided in?

    This item is provided in "Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "NR2B Antibody : HRP (OASE00185-HRP)"?

    This target may also be called "GluN2B" in publications.

  5. What is the shipping cost for "NR2B Antibody : HRP (OASE00185-HRP)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "NR2B Antibody : HRP (OASE00185-HRP)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "NR2B Antibody : HRP (OASE00185-HRP)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "NR2B Antibody : HRP (OASE00185-HRP)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "GRIN2B"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "GRIN2B"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "GRIN2B"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "GRIN2B"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "GRIN2B"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "GRIN2B"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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