Catalog No: OPCD05070
Price: $0.00
SKU
OPCD05070
Availability: Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery
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Datasheets/Manuals | Printable datasheet for NR1H3 Recombinant Protein (OPCD05070) |
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Predicted Species Reactivity | Bos taurus|Bovine |
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Product Format | Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose. |
Host | E.coli |
Conjugation | Unconjugated |
Application | Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot |
Additional Information | Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) |
:: | Residues: Asn95-Lys434 |
:: | Subcellular Location: Nucleus |
Reconstitution and Storage | 2°C to 8°C|-80°C |
Concentration | 200 ug/mL (prior to lyoph) |
Purity | > 97% |
Source | E.coli |
Tag | N-terminal His Tag |
Gene Symbol | NR1H3 |
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Gene Full Name | nuclear receptor subfamily 1 group H member 3 |
Alias Symbols | liver X receptor alpha;LXRalpha;nuclear orphan receptor LXR-alpha;Nuclear receptor subfamily 1 group H member 3;oxysterols receptor LXR-alpha. |
NCBI Gene Id | 507176 |
Protein Name | Oxysterols receptor LXR-alpha |
Description of Target | Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity. Interaction with retinoic acid receptor (RXR) shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity). |
Uniprot ID | Q5E9B6 |
Protein Accession # | NP_001014861.1 |
Nucleotide Accession # | NM_001014861.1 |
Protein Size (# AA) | Asn95~Lys434 |
Molecular Weight | 41kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
-
See our General FAQ page.
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