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NR1H2 Antibody (OALA03039)

50 ug
$539.00
In Stock
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Predicted Species Reactivity:
Dog, Pig, Rat
Product Format:
Liquid
Clonality:
Polyclonal
Host:
Goat
Application:
IHC-P, WB
Reconstitution and Storage:
Store at -20C. Minimize freezing and thawing.
Gene Symbol:
NR1H2
NCBI Gene Id:
7376
Swissprot Id:
P55055
Protein Accession #:
NP_009052.3
Nucleotide Accession #:
NM_007121
Alias Symbols:
NR1H2, Liver X receptor beta, LXR beta, LXR-b, LXRB, Lxrbeta, NER, Nuclear receptor NER, LX receptor beta, Ubiquitous receptor, RIP15, Liver X nuclear receptor beta, NER-I, Oxysterols receptor LXR-beta, UNR
Replacement Item:
This antibody may replace item sc-1000 from Santa Cruz Biotechnology.
Purification:
Immunoaffinity purified
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express NR1H2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express NR1H2.
Immunogen:
NR1H2 / LXR Beta antibody was raised against synthetic peptide SSPTTSSLDTPLPGC from the N-terminus of human NR1H2 (NP_009052.3). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%); Marmoset, Rat, Panda, Dog, Pig (93%); Monkey, Mouse, Hamster, Elephant, Rabbit (86%).
Predicted Homology Based on Immunogen Sequence:
Dog; Pig: 90%; Rat
Concentration:
0.5 mg/ml
Datasheets/Manuals:
Printable datasheet for OALA03039
Specificity:
NR1H2. Based on the peptide used, this antibody is expected to be specific for LXR beta and not to cross-react with LXR alpha.
Epitope:
N-Terminus
Warning:
For research use only.
Application Info:
IHC - Paraffin (3 ug/ml), Western blot (1 - 3 ug/ml), ELISA (1:64000)
Application Data:
Immunohistochemistry: OALA03039 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for OALA03039 was determined to be 3 ug/ml.
Storage Buffer:
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide

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