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- $55: Antibody & Protein in US
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- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for NR1H2 Antibody (OACD00691) |
|---|
| Tested Species Reactivity | Mouse |
|---|---|
| Predicted Species Reactivity | Human|Mouse|Porcine|Rat |
| Product Format | Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Application | Immunocytochemistry|Immunohistochemistry|Immunoprecipitation|Western blot |
| Reconstitution and Storage | 2°C to 8°C|-20°C |
| Immunogen | Recombinant LXRb (Met1~Glu446) expressed in E.coli |
| Purification | Affinity Purified; Protein A Purified |
| Concentration | 0.47 mg/ml |
| Specificity | The antibody is a rabbit polyclonal antibody raised against LXRb. It has been selected for its ability to recognize LXRb in immunohistochemical staining and western blotting. |
| Application Info | WB: 0.5-2 ug/mL IHC: 5-20 ug/mL ICC: 5-20 ug/mL |
| Gene Symbol | Nr1h2 |
|---|---|
| Gene Full Name | nuclear receptor subfamily 1, group H, member 2 |
| Alias Symbols | AI194859;liver X receptor beta;LX;LXR;LXR beta;LXRB;LXRbeta;LXRBSV;NER1;Nuclear receptor subfamily 1 group H member 2;OR-1;oxysterols receptor LXR-beta;retinoid X receptor-interacting protein No.15;RI;RIP15;Ubiquitously-expressed nuclear receptor;ubiquitously-expressed nuclear receptor 2;Un;Unr;Unr2;UR. |
| NCBI Gene Id | 22260 |
| Protein Name | Oxysterols receptor LXR-beta |
| Description of Target | Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity (PubMed:18055760, PubMed:19520913, PubMed:20427281). Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4) (PubMed:18055760, PubMed:19520913, PubMed:20427281). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8; DLDLR and LRP8 (PubMed:18055760, PubMed:19520913, PubMed:20427281). Interplays functionally with RORA for the regulation of genes involved in liver metabolism (PubMed:18055760, PubMed:19520913, PubMed:20427281). Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex (By similarity). |
| Uniprot ID | Q60644 |
| Protein Accession # | NP_001272446.1 |
| Nucleotide Accession # | NM_001285517 |
| Molecular Weight | 50 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "NR1H2 Antibody (OACD00691)"?
The tested species reactivity for this item is "Mouse". This antibody is predicted to have homology to "Human|Mouse|Porcine|Rat".
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How long will it take to receive "NR1H2 Antibody (OACD00691)"?
This item is available "Domestic: within 1-2 weeks delivery | International: within 1-2 weeks delivery".
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What buffer format is "NR1H2 Antibody (OACD00691)" provided in?
This item is provided in "Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "NR1H2 Antibody (OACD00691)"?
This target may also be called "AI194859;liver X receptor beta;LX;LXR;LXR beta;LXRB;LXRbeta;LXRBSV;NER1;Nuclear receptor subfamily 1 group H member 2;OR-1;oxysterols receptor LXR-beta;retinoid X receptor-interacting protein No.15;RI;RIP15;Ubiquitously-expressed nuclear receptor;ubiquitously-expressed nuclear receptor 2;Un;Unr;Unr2;UR." in publications.
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What is the shipping cost for "NR1H2 Antibody (OACD00691)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "NR1H2 Antibody (OACD00691)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "NR1H2 Antibody (OACD00691)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "50 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "NR1H2 Antibody (OACD00691)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "Nr1h2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "Nr1h2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "Nr1h2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "Nr1h2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "Nr1h2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "Nr1h2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
