Catalog No: OAAN00109
Price: $0.00
SKU
OAAN00109
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for anti-NOTCH2 (OAAN00109)
Product Info
Predicted Species ReactivityHuman, Mouse
Product FormatLiquid
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationWB, IHC
Reconstitution and StorageStore at -20C. Avoid repeated freeze/thaw cycles.
ImmunogenRecombinant protein of human NOTCH2
PurificationAffinity purified against immunogen
Preservative0.02% Sodium Azide
Application InfoWB: 1:500 - 1:2,000. IHC: 1:100 - 1:200
Storage BufferPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Gene SymbolNOTCH2
Gene Full Namenotch 2
Alias SymbolshN2, AGS2, HJCYS
NCBI Gene Id4853
Protein NameNeurogenic locus notch homolog protein 2
Description of TargetThis gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene.
Uniprot IDQ04721
Protein Accession #NP_001186930.1
Nucleotide Accession #NM_001200001.1
Molecular Weight265 kDa
  1. What is the species homology for "NOTCH2 Antibody (OAAN00109)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".

  2. How long will it take to receive "NOTCH2 Antibody (OAAN00109)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "NOTCH2 Antibody (OAAN00109)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "NOTCH2 Antibody (OAAN00109)"?

    This target may also be called "hN2, AGS2, HJCYS" in publications.

  5. What is the shipping cost for "NOTCH2 Antibody (OAAN00109)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "NOTCH2 Antibody (OAAN00109)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "NOTCH2 Antibody (OAAN00109)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "265 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "NOTCH2 Antibody (OAAN00109)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "NOTCH2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "NOTCH2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "NOTCH2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "NOTCH2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "NOTCH2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "NOTCH2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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