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Norrin Antibody (OAPB00865)

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0.1 mg
$375.00
In Stock
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Conjugation Options

OAPB00865-FITC Conjugated

OAPB00865-HRP Conjugated

OAPB00865-Biotin Conjugated

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Predicted Species Reactivity:
Human
Clonality:
Polyclonal
Host:
Rabbit
Application:
ELISA, WB, ICC
:::
Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and Storage:
Norrin antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Gene Symbol:
NDP
NCBI Gene Id:
4693
Protein Name:
Norrin
Swissprot Id:
Q00604
Alias Symbols:
ND, EVR2, FEVR,
Description of Target:
Norrie disease protein
Molecular Weight:
Predicted: 26 kDa
Observed: 28 kDa
Purification:
Affinity chromatography purified via peptide column
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express NDP.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express NDP.
Immunogen:
The immunogen for anti-Norrin antibody: antibody was raised against an 18 amino acid peptide from near the amino terminus of human Norrin.
Predicted Homology Based on Immunogen Sequence:
Human
Blocking Peptide:
For anti-Norrin antibody is Catalog # OEPB02985
Datasheets/Manuals:
Printable datasheet for anti-Norrin antibody - OAPB00865
Application Info:
Norrin antibody can be used for detection of Norrin by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
Other Applications Image 1 Data:
Immunocytochemistry of Norrin in Jurkat cells with Norrin antibody at 5 ug/mL.
Target Reference:
Bergen W, Meindl A, van de Pol TJ, et al. Isolation of a candidate gene for Norrie disease by positional cloning. Nat. Genet.1992; 1:199-203.;Meitinger T, Meindl A, Bork P, et al. Molecular modelling of the Norrie disease protein predicts a cysteine knot growth factor tertiary structure. Nat. Genet.1993; 5:376-80.;Xu Q, Wang Y, Dabdoub A, et al. Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair. Cell2004; 116:883-95.;Ohlmann A, Scholz M, Goldwich A, et al. Ectopic norrin induces growth of ocular capillaries and restores normal retinal angiogenesis. J. Neurosci.2005; 25:1701-10.

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