Norrin Antibody : HRP (OAPB00865-HRP)

Catalog No: OAPB00865-HRP

Size:0.1 mg

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Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: HRP: Horseradish Peroxidase
• Application: ELISA, WB, ICC
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen for anti-Norrin antibody: antibody was raised against an 18 amino acid peptide from near the amino terminus of human Norrin.
• Purification: Affinity chromatography purified via peptide column
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: 0.6-0.7 mg/ml
• Blocking Peptide: For anti-Norrin antibody is Catalog # OEPB02985
• Application Info: Norrin antibody can be used for detection of Norrin by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
• Reference: Bergen W, Meindl A, van de Pol TJ, et al. Isolation of a candidate gene for Norrie disease by positional cloning. Nat. Genet.1992; 1:199-203.;Meitinger T, Meindl A, Bork P, et al. Molecular modelling of the Norrie disease protein predicts a cysteine knot growth factor tertiary structure. Nat. Genet.1993; 5:376-80.;Xu Q, Wang Y, Dabdoub A, et al. Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair. Cell2004; 116:883-95.;Ohlmann A, Scholz M, Goldwich A, et al. Ectopic norrin induces growth of ocular capillaries and restores normal retinal angiogenesis. J. Neurosci.2005; 25:1701-10.

Target Info

• Gene Symbol: NDP
• Alias Symbols: ND, EVR2, FEVR
• NCBI Gene Id: 4693
• Protein Name: Norrin
• Description of Target: Norrie disease protein
• Uniprot ID: Q00604
• Molecular Weight: Predicted: 26 kDa
  Observed: 28 kDa