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Catalog No: ARP46892_P050
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ARP46892_P050
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Datasheets/ManualsPrintable datasheet for anti-NNT (ARP46892_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human NNT
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Peptide SequenceSynthetic peptide located within the following region: IVRGFDTRAAALEQFKSLGAEPLEVDLKESGEGQGGYAKEMSKEFIEAEM
Concentration0.5 mg/ml
Blocking PeptideFor anti-NNT (ARP46892_P050) antibody is Catalog # AAP46892 (Previous Catalog # AAPP27688)
ReferenceMehrle,A., Nucleic Acids Res. 34 (DATABASE ISSUE), D415-D418 (2006)
Gene SymbolNNT
Gene Full NameNicotinamide nucleotide transhydrogenase
Alias SymbolsGCCD4
NCBI Gene Id23530
Protein NameNAD(P) transhydrogenase, mitochondrial
Description of TargetNNT is an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants, encoding the same protein, have been found for this gene.
Uniprot IDQ13423
Protein Accession #NP_036475
Nucleotide Accession #NM_012343
Protein Size (# AA)1086
Molecular Weight114kDa
Protein InteractionsMVP; UBC; TIMM10; PTCD1; FKBP8; POFUT1; UQCR11; ATP6V1F; PRPF3; LAMTOR3; SF1; THY1; ABCD3; NDUFS6; NDUFA9; SLC26A2; ATP5B; SLC25A6; SIRT7; MME; HNRNPA1;
  1. What is the species homology for "NNT Antibody - N-terminal region (ARP46892_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".

  2. How long will it take to receive "NNT Antibody - N-terminal region (ARP46892_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "NNT Antibody - N-terminal region (ARP46892_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "NNT Antibody - N-terminal region (ARP46892_P050)"?

    This target may also be called "GCCD4" in publications.

  5. What is the shipping cost for "NNT Antibody - N-terminal region (ARP46892_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "NNT Antibody - N-terminal region (ARP46892_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "NNT Antibody - N-terminal region (ARP46892_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "114kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "NNT Antibody - N-terminal region (ARP46892_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "NNT"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "NNT"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "NNT"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "NNT"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "NNT"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "NNT"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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