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Catalog No: ARP37361_P050
Price: $0.00
SKU
ARP37361_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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Datasheets/ManualsPrintable datasheet for anti-Nmral1 (ARP37361_P050) antibody
Product Info
Tested Species ReactivityMouse
Predicted Species ReactivityMouse, Rat, Cow, Dog, Pig
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the n terminal region of mouse Nmral1
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 79%; Dog: 79%; Mouse: 100%; Pig: 86%; Rat: 86%
Peptide SequenceSynthetic peptide located within the following region: GATGAQGGSVARALLEDGTFRIRVVTRNPEQRAAKELKQQGAEVVRGDQD
Concentration0.5 mg/ml
Blocking PeptideFor anti-Nmral1 (ARP37361_P050) antibody is Catalog # AAP37361 (Previous Catalog # AAPP09536)
Gene SymbolNmral1
Gene Full NameNmrA-like family domain containing 1
Alias SymbolsAI256624, 1110025F24Rik
NCBI Gene Id67824
Protein NameNmrA-like family domain-containing protein 1
Description of TargetNmral1 is a redox sensor protein. Nmral1 undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP+ levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH.Nmral1 has higher affinity for NADPH than for NADP+. Binding to NADPH is necessary to form a stable dimer.
Uniprot IDQ8K2T1
Protein Accession #NP_080669
Nucleotide Accession #NM_026393
Protein Size (# AA)309
Molecular Weight34kDa
  1. What is the species homology for "Nmral1 Antibody - N-terminal region (ARP37361_P050)"?

    The tested species reactivity for this item is "Mouse". This antibody is predicted to have homology to "Mouse, Rat, Cow, Dog, Pig".

  2. How long will it take to receive "Nmral1 Antibody - N-terminal region (ARP37361_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "Nmral1 Antibody - N-terminal region (ARP37361_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Nmral1 Antibody - N-terminal region (ARP37361_P050)"?

    This target may also be called "AI256624, 1110025F24Rik" in publications.

  5. What is the shipping cost for "Nmral1 Antibody - N-terminal region (ARP37361_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Nmral1 Antibody - N-terminal region (ARP37361_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Nmral1 Antibody - N-terminal region (ARP37361_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "34kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Nmral1 Antibody - N-terminal region (ARP37361_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "NMRAL1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "NMRAL1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "NMRAL1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "NMRAL1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "NMRAL1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "NMRAL1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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