NMNAT1 Antibody (OAPA00350)

Catalog No: OAPA00350 (Formerly GWB-BSP850)

Size:5ug

Product Info

• Predicted Species Reactivity: Human
• Product Format: 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
• Clonality: Monoclonal
• Clone: PAT4A2AT
• Isotype: Mouse IgG2b heavy chain and kappa light chain.
• Host: Mouse
• Application: WB
  Product Introduction: NMNAT1 enzyme is vital for NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD. NMNAT1 is widely expressed with high levels in skeletal muscle, heart, liver and kidney. This protein appears to have the ability to protect against axonal degeneration following mechanical or toxic insults.
• Reconstitution and Storage: For periods up to 1 month store at 4C, for longer periods of time, store at -20C. Prevent freeze thaw cycles.
  Stability: 12 months at -20C. 1 month at 4C.
• Immunogen: The immunogen for anti-NMNAT1 antibody: anti-human NMNAT1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human NMNAT1 amino acids 1-279 purified from E. coli.
• Predicted Homology Based on Immunogen Sequence: Human
• Purity: NMNAT1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
• Application Info: NMNAT1 antibody has been tested by ELISA and Western blot analyses to assure specificity and reactivity. Since applications vary, each investigation should be titrated by a reagent to obtain optimal results. Recommended dilution range for Western blot is 1:500 ~ 1000. Recommended starting dilution is 1:500.

Target Info

• Gene Symbol: NMNAT1
• Alias Symbols: LCA9, NMNAT, PNAT1, SHILCA
• NCBI Gene Id: 64802
• Protein Name: Nicotinamide mononucleotide adenylyltransferase 1
• Description of Target: Mouse Anti Human Nicotinamide Nucleotide Adenylyltransferase 1
• Uniprot ID: Q9HAN9