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NGFR Antibody (OAAB21927)

  • Catalog#: OAAB21927
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Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% glycerol
Clonality:
Polyclonal
Host:
Rabbit
Application:
FC, WB, IHC-P, IF
:::
Cellular Location: Membrane; Single-pass type I membrane protein.
Reconstitution and Storage:
Store at -20C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least two weeks at 2-4C.
Gene Symbol:
NGFR
Official Gene Full Name:
nerve growth factor receptor
NCBI Gene Id:
24596
Swissprot Id:
P07174
Protein Accession #:
NP_036742.2
Nucleotide Accession #:
NM_012610.2
Alias Symbols:
p75, LNGFR, p75NTR, RNNGFRR, Tnfrsf16
Replacement Item:
This antibody may replace item sc-13577, HPA004765
Description of Target:
Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake. Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic genes involved in glucose and lipid metabolism in the liver.
Molecular Weight:
45 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express NGFR.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express NGFR.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-NGFR (OAAB21927) antibody
Application Info:
FC: 1:20~100
WB: 1:100~500
IHC-P: 1:100~500
IF: 1:100~200

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