Size:100 ul
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More Information
Predicted Species Reactivity Human, Mouse, Rat
Product Format Liquid 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% glycerol
Clonality Polyclonal
Host Rabbit
Application FC, WB, IHC-P, IF
:: Cellular Location: Membrane; Single-pass type I membrane protein.
Reconstitution and Storage Store at -20C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least two weeks at 2-4C.
Replacement Item This antibody may replace item sc-13577, HPA004765
Concentration 1 mg/ml
Datasheets/Manuals Printable datasheet for anti-NGFR (OAAB21927) antibody
Application Info FC: 1:20~100
WB: 1:100~500
IHC-P: 1:100~500
IF: 1:100~200
Gene Symbol NGFR
Official Gene Full Name nerve growth factor receptor
Alias Symbols p75, LNGFR, p75NTR, RNNGFRR, Tnfrsf16
NCBI Gene Id 24596
Description of Target Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake. Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic genes involved in glucose and lipid metabolism in the liver.
Swissprot Id P07174
Protein Accession # NP_036742.2
Nucleotide Accession # NM_012610.2
Molecular Weight 45 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express NGFR.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express NGFR.
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