Catalog No: ARP38748_P050
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ARP38748_P050
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Datasheets/ManualsPrintable datasheet for anti-NFYB (ARP38748_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human NFYB
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Complete computational species homology dataAnti-NFYB (ARP38748_P050)
Peptide SequenceSynthetic peptide located within the following region: MTMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHEDTNGSKE
Concentration0.5 mg/ml
Blocking PeptideFor anti-NFYB (ARP38748_P050) antibody is Catalog # AAP38748 (Previous Catalog # AAPP20954)
Subunitbeta
ReferenceKimura,K., (2006) Genome Res. 16 (1), 55-65
Gene SymbolNFYB
Gene Full NameNuclear transcription factor Y, beta
Alias SymbolsHAP3, CBF-A, CBF-B, NF-YB
NCBI Gene Id4801
Protein NameNuclear transcription factor Y subunit beta
Description of TargetNFYB is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants.The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants.
Swissprot IdP25208
Protein Accession #NP_006157
Nucleotide Accession #NM_006166
Protein Size (# AA)207
Molecular Weight23kDa
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express NFYB.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express NFYB.
Protein InteractionsAGTRAP; POLE4; DRAP1; NFYA; LYN; CDK2; CCNE1; CCNA2; TP53; SMYD3; NFYC; MAOB; UBC; CREBBP; SP1; HDAC1; EP300; KAT2B; TP73; TAF12; TAF11; TAF6; GRB2; YBX3; CEBPZ; C1QBP; TBP; CIITA; CNTN2; MYC; ELF1; YBX1;
  1. What is the species homology for "NFYB Antibody - N-terminal region (ARP38748_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit".

  2. How long will it take to receive "NFYB Antibody - N-terminal region (ARP38748_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "NFYB Antibody - N-terminal region (ARP38748_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "NFYB Antibody - N-terminal region (ARP38748_P050)"?

    This target may also be called "HAP3, CBF-A, CBF-B, NF-YB" in publications.

  5. What is the shipping cost for "NFYB Antibody - N-terminal region (ARP38748_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "NFYB Antibody - N-terminal region (ARP38748_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "NFYB Antibody - N-terminal region (ARP38748_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "23kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "NFYB Antibody - N-terminal region (ARP38748_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "NFYB"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "NFYB"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "NFYB"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "NFYB"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "NFYB"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "NFYB"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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