Catalog No: P100940_P050-HRP
Size:100ul
Price: $434.00
SKU
P100940_P050-HRP
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NFKBIA Antibody - N-terminal region : HRP (P100940_P050-HRP)

Datasheets/ManualsPrintable datasheet for anti-NFKBIA (P100940_P050-HRP) antibody
Product Info
Predicted Species ReactivityHuman, Pig
Product FormatLiquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
ClonalityPolyclonal
HostRabbit
ConjugationHRP: Horseradish Peroxidase
ApplicationWB, IHC
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human NFKBIA
Predicted Homology Based on Immunogen SequenceHuman: 100%; Pig: 76%
Peptide SequenceSynthetic peptide located within the following region: MFQAAERPQEWAMEGPRDGLKKERLLDDRHDSGLDSMKDEEYEQMVKELQ
Concentration0.5 mg/ml
Blocking PeptideFor anti-NFKBIA (P100940_P050-HRP) antibody is Catalog # AAP31294 (Previous Catalog # AAPP02043)
ReferenceJanssen,R., et al., (2004) J. Exp. Med. 200 (5), 559-568
Gene SymbolNFKBIA
Gene Full NameNuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
Alias SymbolsIKBA, MAD-3, NFKBI, EDAID2
NCBI Gene Id4792
Protein NameNF-kappa-B inhibitor alpha
Description of TargetNFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).
Uniprot IDP25963
Protein Accession #NP_065390
Nucleotide Accession #NM_020529
Protein Size (# AA)317
Molecular Weight36kDa
Protein InteractionsBTRC; NEDD9; IKBKB; CHUK; UBC; MTOR; IKBKG; SKP1; FBXW11; UBE2D3; RELA; NPLOC4; VCP; UFD1L; NFKB1; TNF; SUMO1; UBE2D1; COPS3; GPS1; SUMO3; Csnk2b; PRKCA; ST7; STAT1; REL; POLR2C; CD7; ARRB2; ARRB1; SUMO2; PSMA1; ZNF212; IKZF4; ATF4; TBK1; IKBKE; DNAJA3; S
  1. What is the species homology for "NFKBIA Antibody - N-terminal region : HRP (P100940_P050-HRP)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Pig".

  2. How long will it take to receive "NFKBIA Antibody - N-terminal region : HRP (P100940_P050-HRP)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "NFKBIA Antibody - N-terminal region : HRP (P100940_P050-HRP)" provided in?

    This item is provided in "Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "NFKBIA Antibody - N-terminal region : HRP (P100940_P050-HRP)"?

    This target may also be called "IKBA, MAD-3, NFKBI, EDAID2" in publications.

  5. What is the shipping cost for "NFKBIA Antibody - N-terminal region : HRP (P100940_P050-HRP)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "NFKBIA Antibody - N-terminal region : HRP (P100940_P050-HRP)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "NFKBIA Antibody - N-terminal region : HRP (P100940_P050-HRP)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "36kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "NFKBIA Antibody - N-terminal region : HRP (P100940_P050-HRP)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "NFKBIA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "NFKBIA"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "NFKBIA"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "NFKBIA"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "NFKBIA"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "NFKBIA"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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