Search Antibody, Protein, and ELISA Kit Solutions

NFKB2 Antibody (OASG04980)

100 uL
$215.00
In Stock
Request Bulk Order Quote

Predicted Species Reactivity:
Human, Mouse, Rat
Product Format:
Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
WB, IHC
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Replacement Item:
This antibody may replace item sc-114, HPA008422
Immunogen:
Synthesized peptide derived from human NFKappaB-p100 around the non-phosphorylation site of S869. Location: 810-890aa.
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-NFKB2 (OASG04980) antibody
Specificity:
NFKappaB-p100 Polyclonal Antibody detects endogenous levels of NFKappaB-p100 protein.
Application Info:
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;
Gene Symbol:
NFKB2
Official Gene Full Name:
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Alias Symbols:
NFKB2, LYT10, Nuclear factor NF-kappa-B p100 subunit, DNA-binding factor KBF2, H2TF1, Lymphocyte translocation chromosome 10 protein, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, Oncogene Lyt-10, Lyt10
NCBI Gene Id:
4791; 18034;
Description of Target:
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
Swissprot Id:
Q00653, Q9WTK5
Molecular Weight:
96 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express NFKB2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express NFKB2.

Product Reviews

Protocol:
Tips Information:

Tell us what you think about this item!

Write A Review
    Please, wait...