Catalog No: ARP32718_P050
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ARP32718_P050
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Datasheets/ManualsPrintable datasheet for anti-NFKB2 (ARP32718_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human NFKB2
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: LPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQC
Concentration0.5 mg/ml
Blocking PeptideFor anti-NFKB2 (ARP32718_P050) antibody is Catalog # AAP32718 (Previous Catalog # AAPP03732)
Sample Type Confirmation

NFKB2 is strongly supported by BioGPS gene expression data to be expressed in Raji

ReferenceXiao,G., et al., (2004) J. Biol. Chem. 279 (29), 30099-30105
Publications

Tissue-specific transcription profile of cytokine and chemokine genes associated with flavivirus control and non-lethal neuropathogenesis in rabbits. Virology. 494, 1-14 (2016). 27061052

Gene SymbolNFKB2
Gene Full NameNuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Alias Symbolsp52, p100, H2TF1, LYT10, CVID10, LYT-10, NF-kB2, p49/p100
NCBI Gene Id4791
Protein NameNuclear factor NF-kappa-B p100 subunit
Description of TargetNFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.
Uniprot IDQ00653
Protein Accession #NP_002493
Nucleotide Accession #NM_002502
Protein Size (# AA)933
Molecular Weight101kDa
Protein InteractionsFBXW11; UBC; RELB; RELA; REL; NFKB1; CHUK; BCL3; SUMO1; NEDD8; TNFAIP3; BIRC2; EPS8; VCP; UBD; BRRF1; COMMD1; COMMD2; MAP3K14; BTRC; NFKB2; FBXW7; TSG101; IKBKG; SUMO2; DPF2; PSMD11; NFKBIZ; TNIP2; HDAC5; NFKBIB; HDAC4; USP2; NFKBIE; RPL6; IKBKB; TSC22D3;
  1. What is the species homology for "NFKB2 Antibody - N-terminal region (ARP32718_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit".

  2. How long will it take to receive "NFKB2 Antibody - N-terminal region (ARP32718_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "NFKB2 Antibody - N-terminal region (ARP32718_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "NFKB2 Antibody - N-terminal region (ARP32718_P050)"?

    This target may also be called "p52, p100, H2TF1, LYT10, CVID10, LYT-10, NF-kB2, p49/p100" in publications.

  5. What is the shipping cost for "NFKB2 Antibody - N-terminal region (ARP32718_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "NFKB2 Antibody - N-terminal region (ARP32718_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "NFKB2 Antibody - N-terminal region (ARP32718_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "101kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "NFKB2 Antibody - N-terminal region (ARP32718_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "NFKB2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "NFKB2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "NFKB2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "NFKB2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "NFKB2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "NFKB2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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