Size:100 ug
$315.00
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SKU
OACA02427
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More Information
Predicted Species Reactivity Human
Product Format Liquid
Clonality Polyclonal
Isotype IgG
Host Rabbit
Application WB, IHC, CHIP
Reconstitution and Storage Store at 4C for up to one month. For long term storage, aliquot and store at -20C or -80C. Avoid freeze thaw cycles.
Replacement Item This antibody may replace item sc-114, HPA027305
Immunogen Recombinant human Nuclear factor NF-kappa-B p105 subunit protein
Purification Caprylic Acid Ammonium Sulfate Precipitation purified
Predicted Homology Based on Immunogen Sequence Human
Datasheets/Manuals Printable datasheet for anti-NFKB1 (OACA02427) antibody
Specificity Human
Formulation Provided in PBS, pH 7.4, 50% Glycerol, 0.03% Proclin 300
Target Reference [1] The DNA binding subunit of NF-kappa B is identical to factor KBF1 and homologous to the rel oncogene product. Kieran M., Blank V., Logeat F., Vandekerckhove J., Lottspeich F., le Bail O., Urban M.B., Kourilsky P., Baeuerle P.A., Israel A.Cell 62:1007.
Gene Symbol NFKB1
Official Gene Full Name nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
Alias Symbols p50, KBF1, p105, EBP-1, CVID12, NF-kB1, NFKB-p50, NFkappaB, NF-kappaB, NFKB-p105, NF-kappa-B
NCBI Gene Id 4790
Protein Name nuclear factor NF-kappa-B p105 subunit
Description of Target This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.
Swissprot Id P19838
Protein Accession # NP_001158884.1
Nucleotide Accession # NM_001165412.1
Protein Size (# AA) 968
Molecular Weight 105 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express NFKB1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express NFKB1.
  1. What is the species homology for "NFKB1 Antibody (OACA02427)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "NFKB1 Antibody (OACA02427)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "NFKB1 Antibody (OACA02427)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "NFKB1 Antibody (OACA02427)"?

    This target may also be called "p50, KBF1, p105, EBP-1, CVID12, NF-kB1, NFKB-p50, NFkappaB, NF-kappaB, NFKB-p105, NF-kappa-B" in publications.

  5. What is the shipping cost for "NFKB1 Antibody (OACA02427)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "NFKB1 Antibody (OACA02427)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "NFKB1 Antibody (OACA02427)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "105 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "NFKB1 Antibody (OACA02427)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "NFKB1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "NFKB1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "NFKB1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "NFKB1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "NFKB1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "NFKB1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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