NFATC1 Antibody - N-terminal region (ARP59145_P050)

Catalog No: ARP59145_P050

WB Suggested Anti-NFATC1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Human brain

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NFATC1
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Zebrafish: 100%
• Peptide Sequence: Synthetic peptide located within the following region: HVSFYVCNGKRKRSQYQRFTYLPANVPIIKTEPTDDYEPAPTCGPVSQGL
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-NFATC1 (ARP59145_P050) antibody is Catalog # AAP59145

Target Info

• Gene Symbol: NFATC1
• Gene Full Name: Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
• Alias Symbols: NFAT2, NFATc, NF-ATC, NF-ATc1.2
• NCBI Gene Id: 4772
• Protein Name: Nuclear factor of activated T-cells, cytoplasmic 1
• Description of Target: NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
• Uniprot ID: O95644
• Protein Accession #: NP_765976
• Nucleotide Accession #: NM_172388
• Protein Size (# AA): 353
• Molecular Weight: 38kDa
• Protein Interactions: YWHAQ; OGT; PML; GZF1; FOXP3; HDAC4; PIAS1; SUMO1; UBE2I; RPS6KB1; RPS6KA3; HDAC2; HDAC1; HNRNPA1; TUBA1A; KPNB1; HDAC5; KAT2B; EP300; PARP1; HDAC3; PPP3R1; MAPK14; GNB2L1; PRKCA; SPI1; PIM1; EGR2; EGR1;