Size:100 ug
$315.00
In Stock
SKU
OACA02426
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More Information
Predicted Species ReactivityHuman
Product FormatLiquid
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ApplicationWB, IHC, CHIP
Reconstitution and StorageStore at 4C for up to one month. For long term storage, aliquot and store at -20C or -80C. Avoid freeze thaw cycles.
ImmunogenRecombinant human Negative elongation factor B protein
PurificationCaprylic Acid Ammonium Sulfate Precipitation purified
Predicted Homology Based on Immunogen SequenceHuman
Datasheets/ManualsPrintable datasheet for anti-NELFB (OACA02426) antibody
SpecificityHuman
FormulationProvided in PBS, pH 7.4, 50% Glycerol, 0.03% Proclin 300
Target Reference[1] BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations. Ye Q., Hu Y.-F., Zhong H., Nye A.C., Belmont A.S., Li R.J. Cell Biol. 155:911-921 (2001)
Gene SymbolNELFB
Official Gene Full Namenegative elongation factor complex member B
Alias SymbolsCOBRA1, NELF-B
NCBI Gene Id25920
Protein Namenegative elongation factor B
Description of TargetNELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM, Mar 2008]
Swissprot IdQ8WX92
Protein Accession #NP_056271.3
Nucleotide Accession #NM_015456.4
Protein Size (# AA)580
Molecular Weight66 kDa
Tissue ToolFind tissues and cell lines supported by DNA array analysis to express NELFB.
RNA SeqFind tissues and cell lines supported by RNA-seq analysis to express NELFB.
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