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NELFB Antibody (OACA02426)

100 ug
$315.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
WB, IHC, CHIP
Reconstitution and Storage:
Store at 4C for up to one month. For long term storage, aliquot and store at -20C or -80C. Avoid freeze thaw cycles.
Immunogen:
Recombinant human Negative elongation factor B protein
Purification:
Caprylic Acid Ammonium Sulfate Precipitation purified
Predicted Homology Based on Immunogen Sequence:
Human
Datasheets/Manuals:
Printable datasheet for anti-NELFB (OACA02426) antibody
Specificity:
Human
Formulation:
Provided in PBS, pH 7.4, 50% Glycerol, 0.03% Proclin 300
Target Reference:
[1] BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations. Ye Q., Hu Y.-F., Zhong H., Nye A.C., Belmont A.S., Li R.J. Cell Biol. 155:911-921 (2001)
Gene Symbol:
NELFB
Official Gene Full Name:
negative elongation factor complex member B
Alias Symbols:
COBRA1, NELF-B
NCBI Gene Id:
25920
Protein Name:
negative elongation factor B
Description of Target:
NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM, Mar 2008]
Swissprot Id:
Q8WX92
Protein Accession #:
NP_056271.3
Nucleotide Accession #:
NM_015456.4
Protein Size (# AA):
580
Molecular Weight:
66 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express NELFB.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express NELFB.

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