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Catalog No: OPCD06540
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SKU
OPCD06540
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Datasheets/ManualsPrintable datasheet for NECTIN2 Recombinant Protein (OPCD06540)
Product Info
Predicted Species ReactivityMouse|Mus musculus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Ser83-Ser291
::Subcellular Location: Cell membrane; Singl
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolNectin2
Gene Full Namenectin cell adhesion molecule 2
Alias SymbolsAI325026;AI987993;Cd112;herpes virus entry mediator B;herpesvirus entry mediator B;hveB;mHveB;MP;MPH;murine herpes virus entry protein B;murine herpesvirus entry protein B;necti;Nectin cell adhesion molecule 2;nectin-2;P;poliovirus receptor homolog;poliovirus receptor-related 2;poliovirus receptor-related protein 2;poliovirus sensitivity;Pvr;Pvrl2;Pvs.
NCBI Gene Id19294
Protein NameNectin-2
Description of TargetModulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. Probable cell adhesion protein.
Uniprot IDP32507
Protein Accession #NP_001153196.1
Nucleotide Accession #NM_001159724.1
Protein Size (# AA)Ser83~Ser291
Molecular Weight31kDa
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