NECTIN2 Recombinant Protein (OPCD06539)

Catalog No: OPCD06539

NECTIN2 Recombinant Protein (OPCD06539) using SDS-PAGE

NECTIN2 Recombinant Protein (OPCD06539) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Pro76-Ala353
  Subcellular Location: Cell membrane; Single-pass type I membrane prote
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: NECTIN2
• Gene Full Name: nectin cell adhesion molecule 2
• Alias Symbols: CD112;Herpes virus entry mediator B;herpesvirus entry protein B;HVEB;Nectin cell adhesion molecule 2;nectin-2;poliovirus receptor-like 2;poliovirus receptor-related 2 (herpesvirus entry mediator B);Poliovirus receptor-related protein 2;PRR2;PVRL2;PVRR2.
• NCBI Gene Id: 5819
• Protein Name: Nectin-2
• Description of Target: Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive (PubMed:26755705). Probable cell adhesion protein (PubMed:9657005).
• Uniprot ID: Q92692
• Protein Accession #: NP_001036189.1
• Nucleotide Accession #: NM_001042724.1
• Protein Size (# AA): Pro76~Ala353
• Molecular Weight: 40kDa