NCS1 Protein (OPPA02335)

Catalog No: OPPA02335 (Formerly GWB-BSP549)

Size:5UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: The NCS1 solution contains 20mM Tris-HCl pH-8, 1mM DTT, and 10% glycerol. Physical appearance: Sterile Filtered clear colorless solution.
• Host: E. Coli
  Product Introduction: NCS1 is part of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed primarily in neurons. NCS1 regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. NCS1 is related with secretory granules and modulates synaptic transmission and synaptic plasticity. NCS1 regulates GRK1 and substitutes for calmodulin. NCS1 stimulates PI4KB kinase activity and participates in long-term synaptic plasticity through its interaction with PICK1. NCS1 takes part in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel.
  Product Description: NCS1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 198 amino acids (1-190 a.a.) and having a molecular mass of 22.9 kDa. The NCS1 is fused to an 8 amino acid His Tag at C-Terminus and purified by proprietary chromatographic techniques.
• Reconstitution and Storage: NCS1 Recombinant Human although stable at 4C for 30 days, should be stored desiccated below -20C for periods greater than 30 days. Please avoid freeze-thaw cycles.
• Purity: Greater than 95% as determined by SDS-PAGE.
• Peptide Sequence: MGKSNSKLKP EVVEELTRKT YFTEKEVQQW YKGFIKDCPS GQLDAAGFQK IYKQFFPFGD PTKFATFVFN VFDENKDGRI EFSEFIQALS VTSRGTLDEK LRWAFKLYDL DNDGYITRNE MLDIVDAIYQ MVGNTVELPE EENTPEKRVD RIFAMMDKNA DGKLTLQEFQ EGSKADPSIV QALSLYDGLV LEHHHHHH.

Target Info

• Gene Symbol: NCS1
• Alias Symbols: FLUP, FREQ
• NCBI Gene Id: 23413
• Protein Name: Neuronal calcium sensor 1
• Description of Target: Recombinant Human Neuronal Calcium Sensor 1
• Uniprot ID: P62166
• Protein Accession #: NP_001122298.1
• Protein Size (# AA): Recombinant